关键词: 　先天性心脏病；　动脉导管未闭；　室间隔缺损封堵器

Abstract: Objectives　To explore the clinical efficacy of ventricular septal defect (VSD) occluder in the treatment of peculiar shaped patent ductus arteriosus (PDA) in infants. Methods　The clinical data in 27 children with window-type PDA or tubular-type PDA (arterial catheter length >7 mm) diagnosed by aortic arch angiography and having interventional treatment of VSD occluder from July 2017 to July 2018 were analyzed. Results　There were 12 window-type PDA patients (7 boys and 5 girls) with a median age of 8.7 months (6 months to 3 years), and 15 tubular-type PDA patients (6 boys and 9 girls) with a median age of 18 months (11 months to 5 years). The window-type PDA was occluded with membranous ventricular septal defect occluder, and the tubular-type PDA was occluded by muscular ventricular septal defect occluder. The waist size of occluder was selected according to the pulmonary artery end diameter plus 3~6 mm for window- type PDA and plus 2~4 mm for tubular-type PDA. All children were successfully occluded, and there was no residual shunt after operation. Chest X-ray examination at 24 hours, 1 month, 3 months, 6 months and 12 months after operation showed that the occluder were in good position. The descending aorta blood flow rate at 24 hours, 1 month, 3 months, 6 months and 12 months after operation was significantly lower than that before operation, and the difference was statistically significant (P<0.05). Compared with preoperative data, postoperative left pulmonary artery flow velocity did not change, and the difference was not statistically significant (P>0.05). Conclusion　VSD occluder is an effective and feasible method for interventional treatment of special shaped PDA.

Key words: congenital heart disease;　patent ductus arteriosus;　ventricular septal defect occluder