Journal of Clinical Pediatrics ›› 2020, Vol. 38 ›› Issue (10): 749-.doi: 10.3969/j.issn.1000-3606.2020.10.007
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LIU Yingli, ZHOU Lin, ZHANG Yonghong, TAN Jintong, ZHAO Dongying, XU Min, XIA Hongping
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Abstract: Objective? To?explore?the?clinical?features?of?metabolic?bone?disease?with?fracture?in?preterm?infants.? Method? The?clinical?data?of?metabolic?bone?disease?with?fractures?in?6?neonates?admitted?from?January?2016?to?April?2020?were? retrospectively?analyzed.?Results? Among?the?6?newborns?(5?boys?and?one?girl),?the?median?gestational?age?was?27.1?weeks,? and?the?median?birth?weight?was?900?g.?Among?the?6?newborns,?multiple?costal?fractures?occurred?in?one?case,?left?humeral? fracture?occurred?in?one?case,?left?femoral?fracture?occurred?in?two?cases,?femoral?and?humeral?fracture?occurred?in?two?cases,? and?right?humeral?fracture?occurred?in?one?case.?The?blood?phosphorus?of?the?6?newborns?were?all?<1.8?mmol/L,?and?the?blood? alkaline?phosphatase?were?all?>600?IU/L,?and?the?blood?calcium?were?in?the?normal?range.?All?the?6?neonates?were?complicated? with?retinopathy?of?prematurity?and?bronchopulmonary?dysplasia,?and?one?was?complicated?with?necrotizing?enterocolitis.?After? active?treatment?with?calcium,?phosphorus?and?vitamin?D3,?6?neonates?were?discharged?from?hospital?after?recovery?from?fracture.? Conclusion? Premature?infants?with?very?low?birth?weight?should?pay?attention?to?avoid?metabolic?osteopathy?complicated?with? fracture.
Key words: metabolic?bone?disease;? fracture;? alkaline?phosphatase;? premature?infant
LIU Yingli, ZHOU Lin, ZHANG Yonghong, et al. Clinical analysis of metabolic bone disease in 6 premature infants with fracture[J].Journal of Clinical Pediatrics, 2020, 38(10): 749-.
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https://jcp.xinhuamed.com.cn/EN/Y2020/V38/I10/749
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