婴幼儿重症百日咳研究进展
收稿日期: 2024-08-05
录用日期: 2024-12-25
网络出版日期: 2025-05-09
基金资助
山西省医学重点科技项目计划(2021XM25)
Research progress on severe pertussis in infants and young children
Received date: 2024-08-05
Accepted date: 2024-12-25
Online published: 2025-05-09
许示沂 , 杜敏 , 白丽霞 , 刘爱红 . 婴幼儿重症百日咳研究进展[J]. 临床儿科杂志, 2025 , 43(5) : 383 -388 . DOI: 10.12372/jcp.2025.24e0793
Pertussis is highly contagious. With the increase in the incidence rate of pertussis in recent years, pertussis outbreaks have even occurred in some areas. The recurrence of pertussis has attracted widespread attention, among which severe pertussis poses a great threat to the life and health of infants and young children. Elevated white blood cell count, pulmonary hypertension, non-vaccination and mixed infection are all associated with severe pertussis. Due to the lack of typical clinical symptoms and signs in infants and young children in the early stage, they often fail to receive timely diagnosis and treatment, which can easily lead to severe pertussis. Therefore, it is crucial to make an accurate diagnosis and provide timely treatment for pertussis. This article reviews the pathogenesis, treatment and prevention of severe pertussis in infants and young children, in order to deepen the clinician's understanding of severe pertussis and provide reference for the prevention and treatment of severe pertussis.
Key words： severe pertussis; pathogenesis; vaccine; infants and young children
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