临床儿科杂志 ›› 2020, Vol. 38 ›› Issue (10): 754-.doi: 10.3969/j.issn.1000-3606.2020.10.008

• 综合报道 • 上一篇    下一篇

以发热、黄疸为首发症状的不完全川崎病2例报告并文献复习

马莹莹, 彭韶, 储卫红, 高艺伟, 张曼, 徐莉燕, 高源, 苗雪艳   

  1. 郑州大学第一附属医院(河南郑州 450052)
  • 出版日期:2020-10-15 发布日期:2020-10-10
  • 通讯作者: 彭韶 电子信箱:pengshaodh630@126.com
  • 基金资助:
    河南省教育厅项目(No. 18A320013)

Incomplete Kawasaki disease with initial symptoms of fever and jaundice: a report of 2 cases and literature review

MA Yingying, PENG Shao, CHU Weihong, GAO Yiwei, ZHANG Man, XU Liyan, GAO Yuan, MIAO Xueyan   

  1. Department of Pediatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
  • Online:2020-10-15 Published:2020-10-10

摘要: 目的 探讨以发热、黄疸为首发症状的不完全川崎病(IKD)的临床特征。方法 回顾分析2例以发热、黄疸 为首发症状的不完全KD患儿的临床资料,并复习相关文献。结果 3岁9个月男性患儿及10岁女性患儿,以发热、皮肤黄染、 淋巴结肿大、球结膜充血为早期主要症状,均无皮疹,后期出现指端、肛周蜕皮,并冠状动脉扩张。其中男性患儿出现动眼 神经麻痹及丙种球蛋白抵抗,女性患儿出现KD休克综合征。结论 以发热、黄疸为首发症状的IKD患儿,可能因症状不 典型而致诊断延迟。

关键词: 黄疸; 不完全川崎病; 川崎病休克综合征; 动眼神经麻痹

Abstract: Objective To?explore?the?clinical?features?of?incomplete?Kawasaki?disease?(IKD)?with?first?symptoms?of? fever?and?jaundice.?Method The?clinical?data?of?incomplete?KD?with?the?first?symptoms?of?fever?and?jaundice?in?2?cases?were? retrospectively?analyzed,?and?relevant?literature?was?reviewed.?Results In?two?patients?(3-year-?and?9-month-old?boy?and?a? 10-year-old?girl),?the?main?early?symptoms?were?fever,?yellowish?skin,?lymphadenopathy?and?bulbar?conjunctival?hyperemia,? and?no?rash.?They?presented?with?periungual?and?perianal?desquamation?and?coronary?artery?ectasia?at?the?later?stage.?The?boy? developed?oculomotor?palsy?and?gamma?globulin?resistance,?and?the?girl?developed?KD?shock?syndrome.?Conclusion The diagnosis?in?IKD?children?with?fever?and?jaundice?as?the?first?symptoms?may?be?delayed?due?to?atypical?symptoms.

Key words:  jaundice;? incomplete?Kawasaki?disease;? Kawasaki?disease?shock?syndrome;? oculomotor?nerve?palsy