Influence of IL-17 on mesangial cell and its molecular mechanism
WANG Li1,3, LI Qiu1, LI Cuicui1, YANG Haiping1, WANG Lijia2, LIU Wei2
(1. Department of Nephrology and Immunology, 2. The Children's Research Institution, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; 3. Department of Neprology, Chengdu Women and Children's Central Hospital, Chengdu 610091, Sichuan, China)
[1] Segerer S，Nelson PJ，Schlondorff D. Chemokines，chemokine receptors，and renal disease：from basic science to pathophysiologic and therapeutic studies [J]. J Am Soc Nephrol, 2000，11(1)：152-176. [2] 王莉，李秋，王莉佳，等. 原发性肾病综合征患儿外周血Th17与CD4+ CD25+ Foxp3+ 调节性T细胞的水平 [J]. 细胞与分子免疫学杂志，2010，26(08)：783-786. [3] Steinmetz OM，Turner JE，Paust HJ，et al. CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis [J]. J Immunol，2009，183(7)：4693-4704. [4] Aggarwal S，Gurney AL. IL-17：prototype member of an emerging cytokine family [J]. J Leukoc Biol，2002，71（1）：1-8. [5] Kawaguchi M，Adachi M，Oda N，et al. IL-17 cytokine family [J]. J Allergy Clin Immunol，2004，114（6）：1265-1273. [6] Shao XS，Yang XQ，Zhao XD，et al. The prevalence of Th17 cells and FOXP3 regulate T cells (Treg) in children with primary nephrotic syndrome [J]. Pediatr Nephrol，2009，24（9）：1683-1690. [7] Huang J，Siragy HM. Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro) renin receptor expression [J]. Endocrino-logy，2009，150(12)：5557-5565. [8] Hong HK，Song CY，Kim BC，et al. ERK contributes to the effects of Smad signaling on oxidized LDL-induced PAI-1 expression in human mesangial cells [J]. Transl Res，2006，148(4)：171-179. [9] Sohn M，Tan Y，Klein RL，et al. Evidence for low-density lipoprotein-induced expression of connective tissue growth factor in mesangial cells [J]. Kidney Int，2005，67(4)：1286-1296. [10] Di Paolo S，Grandaliano G，Gesualdo L，et al. Low-density lipoproteins enhance transforming growth factor-beta 1 (TGF-beta 1) and monocyte chemotactic protein-1 (MCP-1) expression induced by cyclosporin in human mesangial cells [J]. Clin Exp Immunol，1999，117(2)：355-360. [11] Murphy WM, Jukkola AF, Roy S 3rd. Nephrotic syndrome with mesangial-cell proliferation in children-a distinct entity?[J]. Am J Clin Pathol，1979,72(1)：42-47. [12] Diamond JR,Ding G，Frye J，et al . Glomerular macrophages and the mesangial proliferative response in the experimental nephrotic syndrome [J]. Am J Pathol，1992，141(4)：887-894. [13] Fossiez F，Djossou O，Chomarat P,et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines [J]. J Exp Med，1996，183(6)：2593-2603. [14] Paust HJ，Turner JE，Steinmetz OM，et al. The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis [J]. J Am Soc Nephrol，2009，20(5)：969-979. [15] Franzen R，Pautz A，Brautigam L，et al. Interleukin-1beta induces chronic activation and de novo synthesis of neutral ceramidase in renal mesangial cells [J]. J Biol Chem，2001，276(38)：35382-35389. [16] Blume C，Sabuda-Widemann D，Pfeilschifter J，et al. Ceri-vastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide [J]. Eur J Pharmacol，2004，485(1-3)：1-10. [17] Wang R，Wan Q，Zhang Y，et al. Emodin suppresses interleukin-1beta induced mesangial cells proliferation and extracellular matrix production via inhibiting P38 MAPK [J]. Life Sci，2007，80(26)：2481-2488. [18] Shalom-Barak T，Quach J，Lotz M. Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB [J]. J Biol Chem，1998，273(42)：27467-27473. [19] Schwandner R，Yamaguchi K，Cao Z. Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction [J]. J Exp Med，2000，191(7)：1233-1240. [20] Iyoda M，Shibata T，Kawaguchi M，et al. IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells：synergy with TNF-alpha and IL-1beta [J]. Am J Physiol Renal Phy-siol，2010，298(3)：F779-787. [21] Zhang W，Li Q，Wang L，et al. Simvastatin ameliorates glomerulosclerosis in Adriamycin-induced nephropathy rats [J]. Pediatric Nephrol，2008，23(12)：2185-2194. [22] Guijarro C，Egido J. Transcription factor-kappa B (NF-kappa B) and renal disease [J]. Kidney Int，2001，59(2)：415-424.
