›› 2014, Vol. 32 ›› Issue (3): 232-234.

• Original Article • Previous Articles     Next Articles

Value of 99mTc-EC dynamic renography in diagnosis of renal scars in children 

FENG Yang1, SU Xiao2, LI Jianing1    

  1. (1. Department of Nuclear Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China; 2. Department of Radiology, The Third Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 201999, China)
  • Received:2013-09-21 Online:2014-03-15 Published:2014-03-15

Abstract:  Objective To evaluate the diagnostic value of 99mTc-EC dynamic renography for renal scars in children with urinary tract infection. Methods The 99mTc-EC and 99mTc-DMSA renographic results of 67 children diagnosed with urinary tract infection were retrospectively studied. In comparison with 99mTc-DMSA cortical images, the value of 99mTc-EC dynamic renography for the diagnosis of urinary tract infection, hydronephrosis and renal scars was analyzed. Results The sensitivity and specificity of the initial 2 minutes summed images in the 99mTc-EC images for the diagnosis of renal scars was 80.28% and 88.89% respectively, and the likelihood ratio was 7.23. Renal scars were more likely to be formed in patients with obstructed upper urinary tracts, as compared with patients with unobstructed upper urinary tracts and unsmooth upper urinary tracts (P<0.05). The incidence of renal scar formation was not significantly different among groups with hydronephrosis of varying degrees (P>0.05). Conclusions For children with urinary tract infection, the diagnostic sensitivity and specificity of the initial summed images of 99mTc-EC dynamic renography are high. Furthermore, the excretion of upper urinary tract showed by 99mTc-EC dynamic renography is valuable for the diagnosis of renal scars.