›› 2016, Vol. 34 ›› Issue (2): 93-.doi: 10.3969 j.issn.1000-3606.2016.02.003

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 人偏肺病毒|人博卡病毒|呼吸道感染|儿童

 ZHANG Yunhong1, SUN Yu2, JIA Yunxia3, LIU Yan3, LAN Tao3, ZHAO Linqing2, QIAN Yuan2, ZHU Runan2, WANG Naichang4   

  1. 1. Shanxi Medical University, Taiyuan 030001, Shanxi, China; 2. Laboratory of Virology, Capital Institute of Pediatrics, Beijing 100020, China; 3. Department of Pediatrics, People’s Hospital Affiliated to Shanxi Medical University, Taiyuan 030012, Shanxi, China; 4. Laboratory of Virology , Center for Disease Control and Prevention of Shanxi Province, Taiyuan 030012, Shanxi , China
  • Received:2016-02-15 Online:2016-02-15 Published:2016-02-15

Abstract: Objective  To investigate the status and clinical and epidemiological characteristics of human metapneumovirus (hMPV) and human bocavirus (HBoV) infections in children with acute respiratory tract infections (ARTIs) in Taiyuan. Methods A total of 549 children with ARTIs from November 2012 to May 2013 and November 2013 to May 2014 were recruited. The pharyngeal swab specimens were collected. The hMPV and HBoV were detected by using real-time PCR. Results In 549 children, 56 children (10.2%) were hMPV positive on swab specimens, 15 children (2.7%) were HBoV positive on swab specimens. The detection rates of hMPV and HBoV in November 2012 to May 2013 were 12.3% and 2.0%, respectively, and in November 2013 to May 2014 were 6.5% and 4.0%, respectively. The detection rate of hMPV was significantly different between two periods (P<0.05), while the detection rate of HBoV has no significant difference between two periods. In different months, the detection rate of hMPV and HBoV showed no significant difference. The highest detection rates of hMPV and HBoV were all in children younger than two years old. The highest detection rate of hMPV was in children with asthmatic bronchitis or bronchiolitis. Conclusion In Taiyuan, during the monitoring periods, the ARITS are associated with childhood hMPV and HBoV infection especially in infants and toddlers. hMPV is one of the most important pathogens in infants and toddlers with wheezing.