Abstract: 　Because of the characteristics of the coagulation system and operation for diagnosis and treatment in newborn, arterial thrombosis is easily formed, especially in the limbs. If a newborn's arterial thrombosis is not intervened in time, it may lead to amputation, or even become a threat to life. Thus, early detection and diagnosis have a great impact on the prognosis. Here, we review the diagnosis and treatment of arterial thrombosis in the limbs of the newborn.