Abstract: 　Objective　To explore the clinical characteristics and treatment of pediatric sepsis complicated with splenic abscess. Method　The clinical data of sepsis complicated with splenic abscess in a child was retrospectively analyzed. Relevant literature in CNKI, Wanfang Database, and PubMed was retrieved and analyzed. Results　An 11-month-old boy was mainly characterized by recurrent fever. Blood culture showed Enterococcus faecium infection, and the effect of anti-infection treatment was not ideal. Abdominal ultrasonography and magnetic resonance imaging showed multiple splenic abscesses. After ultrasonic-guided fluid extraction of the abscess, the child still had fever and finally underwent splenic abscess resection. One week after surgery, the child's temperature returned to normal. A total of 15 domestic and foreign literatures were returned by the search, and 59 cases of sepsis complicated with splenic abscess in children were found. The main clinical manifestations were fever, cough, abdominal pain or abdominal distension, and 4 cases had underlying diseases. In them, blood culture was positive in 12 cases, in which 4 were positive for cocci and 8 were positive for bacilli. All the 59 cases were received anti-infective treatment, and 2 cases received antituberculosis treatment at the same time. One case underwent splenocentesis and 5 underwent splenectomy. The prognosis of 55 cases was good, 2 cases were improved and 2 cases had relapse. Conclusion　Fever is the main manifestation in sepsis complicated with splenic abscess in children. Some children have underlying diseases, and anti-infection treatment with sufficient quantity and sufficient duration is the main treatment. Splenic abscess resection should be performed when necessary.

Key words: sepsis;　splenic abscess;　infant