Abstract: Objective　To analyze clinical manifestations and treatment of eosinophilic gastroenteritis (EGE) in children. Methods　The clinical data of 10 children with EGE under the treatment from June 2014 to June 2012 were analyzed retrospectively. Results　There were 10 children (6 males and 4 females) aged from 9 months to 14 years. Clinical symptoms of eight preschool and school age children included abdominal pain (8 cases), vomiting (4 cases), diarrhea (3 cases), ascites (3 cases), rash (3 cases), fever (2 cases) and hypoalbuminemia (2 cases). Clinical symptoms of two infant and toddler were diarrhea and hematochezia. Peripheral blood eosinophils were increased in 10 children. IgE was elevated in 9 children. One child had very high C-reactive protein. Endoscopic examination showed mucosal congestion, swelling, erythema, erosion. Multiple sites of biopsy showed eosinophil count> 20/HP. One child was diagnosed by laparoscopic exploration. The treatment included diet avoidance, omeprazole, anti-allergic drug. Four children were treated with corticosteroids. All children had been followed up for 6 months to 2 years. One child had relapsed. Conclusion　 The clinical manifestations of EGE are various. Endoscopic biopsy is necessary for diagnosis. Laparoscopy also is helpful for diagnosis. Dietary and glucocorticoid therapy were effective.