Analyses of the short-term prognostic factors for recovery of independent walking in Guillain Barre syndrome in children

  • LIANG Jufang ,
  • CHEN Juanjuan ,
  • LUO Xiaoqing ,
  • CUI Ling ,
  • JIANG Jun ,
  • SUN Ruidi ,
  • WANG Xiaolu ,
  • LI Cheng ,
  • LIU Zhisheng
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  • 1. Department of Electrophysiology, Wuhan Children Hospital, Wuhan 421000, Hubei, China; 2. Department of neurology, WuHan children hospital, Wuhan 421000, Hubei, China; 3. Department of pediatric ,ShiYan tai he hospital, Shiyan 44200, Hubei, China

Received date: 2018-03-15

  Online published: 2018-03-15

Abstract

 Objective To explore the prognostic factors in Guillain Barre syndrome (GBS) in children. Methods A total of 125 children with GBS were included and grouped according to their independent walking at two and six months after discharge, and their clinical data were analyzed. Results In 125 children (74 males, 51 females) the average age was 84.49±25.32 months, and 41 were under 6 years old. 102 children had a history of prodromal infections. 32 children had cranial nerve involvement and 35 had autonomic nerve involvement. 12 children need assisted respiration. At 2 and 6 months after discharge, when compared with children who could walk independently, the rates of  functional score > 3, cranial nerve involvement, and neuroelectrophysiology as denervation potential were higher in children who could not walk independently, and the differences were statistically significant (P all<0.05). Conclusions The factors that affect the short-term prognosis are denervation potential in neuroelectrophysiology, cranial nerve involvement, and functional score > 3. Early identification of uniqueness in patients and subsequent development of targeted rehabilitation training should be carried out to improve the prognosis.

Cite this article

LIANG Jufang , CHEN Juanjuan , LUO Xiaoqing , CUI Ling , JIANG Jun , SUN Ruidi , WANG Xiaolu , LI Cheng , LIU Zhisheng . Analyses of the short-term prognostic factors for recovery of independent walking in Guillain Barre syndrome in children[J]. Journal of Clinical Pediatrics, 2018 , 36(3) : 178 . DOI: 10.3969/j.issn.1000-3606.2018.03.005

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