Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder characterized by multiple motor tics and at least one phonic tic. The onset of TS can be caused by a variety of genetic and environmental factors. Most TS comorbid with other psychiatric disorders, such as attention deficit hyperactivity disorder, obsessive-compulsive disorder, etc. Current treatment of TS includes behavioral intervention, pharmacological treatment, surgical treatment, and transcranial magnetic stimulation etc. This article reviews the treatment of TS in children and adolescents.