Objective　To evaluate the clinical value of double-balloon enteroscopy in pediatric patients. Method　Data of 44 patients who underwent double-balloon enteroscopy in our hospital from July 2016 to April 2019 was retrospectively analyzed. Results　The average age of 44 patients was 9.64±3.36 years (the youngest age 2 years and 9 months, the lowest body weight 12.6 kg). Among 44 patients, 25 patients for obscure gastrointestinal bleeding, 16 patients for abdominal pain, 2 patients for diarrhea, and 1 patient for Peutz-Jegher's syndrome.The overall diagnostic yield of 43 patients was 58.14%(25/43). There were 7 patients under the age of 6 (7/44, 15.91%), 4 patients were detected (4/7, 57.14%). The diagnostic yield for obscure gastrointestinal bleeding was 64% (16/25), abdominal pain 50% (8/16) and diarrhea 50%(1/2). The main diseases detected including 14 of ileal diverticulum, 4 of Crohn's disease, and 3 cases of non-specific inflammation of the small intestine (congestion, erosion, ulcer). All patients had no complications such as perforation, severe bleeding, and anesthesia. Conclusion　Doubleballoon enteroscopy is a safe and feasible endoscopic procedure for pediatric patients.