Spontaneous remission of acute monoblastic leukemia in children: a case report and literature review

  • 陈诗杨,袁秀丽,付笑迎,等
Expand
  • 1.Department of Clinical Laboratory, 2.Department of Haematology Oncology, Shenzhen Children’s Hospital, Shenzhen 518038, Guangdong, China

Online published: 2020-07-14

Abstract

 Objective To explore the inducement and possible mechanism of spontaneous remission in acute myeloid leukemia. Method The clinical data of acute monoblastic leukemia in a child with spontaneous remission were reviewed, and the possible mechanism of spontaneous remission was discussed in combination with relevant literature. Results A year and 4 months old boy was diagnosed with acute monoblastic leukemia and had a spontaneous remission without chemotherapy. About 1 year later, the boy relapsed with myeloid sarcoma and received HLA haploidentical hematopoietic stem cell transplantation. The prognosis was good. Previous studies showed that most patients with spontaneous remission had a history of fever that was usually caused by infection, but could also be caused by drug withdrawal or blood transfusion. Conclusion Spontaneous remission of acute myeloid leukemia is extremely rare. Immunotherapy may be employed to treat leukemia in the future.

Cite this article

陈诗杨,袁秀丽,付笑迎,等 . Spontaneous remission of acute monoblastic leukemia in children: a case report and literature review[J]. Journal of Clinical Pediatrics, 2020 , 38(7) : 536 . DOI: 10.3969/j.issn.1000-3606.2020.07.013

Outlines

/