BCG vaccine is the only vaccine currently available for clinical prevention of tuberculosis. Though relatively safe, the common or severe adverse events after BCG and their managements should be paid attention and familiarized by pediatricians. Common abnormal reactions of BCG vaccine include local abscess, lymphadenitis, tuberculid (scleroderma erythema, tinea of the scrotum and papulonecrotic tuberculid), osteomyelitis and systemic disseminated BCG infection. In this paper, the diagnosis and treatment of these common abnormal reactions will be reviewed.