Journal of Clinical Pediatrics >
Diagnostic approach on childhood renal dysfunction
Received date: 2021-07-26
Online published: 2022-02-11
Renal dysfunction refers to a variety of situations, including kidney diseases and other diseases, which cause the increase of creatinine and urea nitrogen, accompanied with edema, electrolyte disorder, hypertension and other multiple system related symptoms in some cases. A large proportion of patients were characterized by renal dysfunction as the primary symptom in children. The author summarized the diagnosis approach on childhood renal dysfunction, suggested that the stage on renal function should be based on the same classification standard as in chronic renal disease. Hereditary disease is the most common cause of renal dysfunction in children. Congenital anomalies of the kidney and urinary tract, which might be mainly results from developmental abnormalities, represent a broad spectrum of disorders.
Key words： renal dysfunction; diagnose approach; child
Hongwen ZHANG . Diagnostic approach on childhood renal dysfunction[J]. Journal of Clinical Pediatrics, 2022 , 40(2) : 155 -159 . DOI: 10.12372/jcp.2022.21e1093
| [1] | Khwaja A. KDIGO clinical practice guidelines for acute kidney injury[J]. Nephron, 2012, 120(4):c179-c184. |
| [2] | Shalaby MA, Sawan ZA, Nawawi E, et al. Incidence, risk factors, and outcome of neonatal acute kidney injury: a prospective cohort study[J]. Pediatr Nephrol, 2018, 33(9):1617-1624. |
| [3] | Gaitonde DY, Cook DL, Rivera IM. Chronic kidney disease: detection and evaluation[J]. Am Fam Physician, 2017, 96(12):776-783. |
| [4] | Barry R, James MT. Guidelines for classification of acute kidney diseases and disorders[J]. Nephron, 2015, 131(4):221-226. |
| [5] | Kidney Disease: Improving Global Outcomes Hepatitis CWG. KDIGO 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C in chronic kidney disease[J]. Kidney Int Suppl (2011), 2018, 8(3):91-165. |
| [6] | National Kidney F. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification[J]. Am J Kidney Dis, 2002, 39(2 Suppl 1):S1-S266. |
| [7] | Chawla LS, Bellomo R, Bihorac A, et al. Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup[J]. Nat Rev Nephrol, 2017, 13(4):241-257. |
| [8] | Akbari A, Clase CM, Acott P, et al. Canadian Society of Nephrology Commentary on the KDIGO clinical practice guideline for CKD evaluation and management[J]. Am J Kidney Dis, 2015, 65(2):177-205. |
| [9] | 张宏文, 丁洁. 遗传性肾病综合征的基因诊断[J]. 临床儿科杂志, 2011, 29(10):990-994. |
| [10] | 崔洁媛, 张宏文. 肾单位肾痨及其相关纤毛病研究进展[J]. 中国生育健康杂志, 2017, 28(2):195-197. |
| [11] | Palevsky PM, Liu KD, Brophy PD, et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury[J]. Am J Kidney Dis, 2013, 61(5):649-672. |
| [12] | 何国华, 张宏文, 王芳, 等. 尿α1微球蛋白与微量白蛋白比值诊断Dent病临床价值研究[J]. 中国实用儿科杂志, 2017, 32(5):371-373. |
| [13] | 张宏文, 张琰琴, 刘晓宇, 等. Dent 病6例临床诊治分析[J]. 临床儿科杂志, 2016, 34(6):418-420. |
| [14] | Murugapoopathy V, Gupta IR. A primer on congenital anomalies of the kidneys and urinary tracts (CAKUT)[J]. Clin J Am Soc Nephrol, 2020, 15(5):723-731. |
| [15] | Kohl S, Habbig S, Weber LT, et al. Molecular causes of congenital anomalies of the kidney and urinary tract (CAKUT)[J]. Mol Cell Pediatr, 2021, 8(1):1-6. |
| [16] | Dyck RF, Karunanayake C, Pahwa P, et al. Congenital anomalies of the kidney and urinary tract (CAKUT): an emerging relationship with pregestational diabetes mellitus among first nations and non-first nations people in saskatchewan-results from the DIP: ORRIIGENSS project[J]. Can J Diabetes, 2021, 45(4):346-354. |
| [17] | Ishiwa S, Sato M, Morisada N, et al. Association between the clinical presentation of congenital anomalies of the kidney and urinary tract (CAKUT) and gene mutations: an analysis of 66 patients at a single institution[J]. Pediatr Nephrol, 2019, 34(8):1457-1464. |
| [18] | Rao J, Liu X, Mao J, et al. Genetic spectrum of renal disease for 1001 Chinese children based on a multicenter registration system[J]. Clin Genet, 2019, 96(5):402-410. |
| [19] | Vivante A, Hildebrandt F. Exploring the genetic basis of early-onset chronic kidney disease[J]. Nat Rev Nephrol, 2016, 12(3):133-146. |
| [20] | Harambat J, van Stralen KJ, Kim JJ, et al. Epidemiology of chronic kidney disease in children[J]. Pediatr Nephrol, 2012, 27(3):363-373. |
| [21] | Navaneethan SD, Zoungas S, Caramori ML, et al. Diabetes management in chronic kidney disease: synopsis of the 2020 KDIGO clinical practice guideline[J]. Ann Intern Med, 2021, 174(3):385-394. |
| [22] | Kidney Disease: Improving Global Outcomes Blood Pressure Work G. KDIGO 2021 clinical practice guideline for the management of blood pressure in chronic kidney disease[J]. Kidney Int, 2021, 99(3S):S1-S87. |
| [23] | Cianciolo G, Cappuccilli M, Tondolo F, et al. Vitamin D effects on bone homeostasis and cardiovascular system in patients with chronic kidney disease and renal transplant recipients[J]. Nutrients, 2021, 13(5):1-22. |
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