Journal of Clinical Pediatrics >
Concerns about diagnosis and treatment of bronchopulmonary dysplasia
Received date: 2022-03-08
Online published: 2022-06-07
Bronchopulmonary dysplasia (BPD) is the commonest chronic lung disease in premature infants, especially in very and extremely low birth weight infant. BPD affects the survival rate and the quality of life of premature infants. At present, the incidence of BPD remains high. With the in-depth understanding of BPD, the diagnostic criteria of BPD are constantly revised, and the treatment methods are constantly improved and perfected. However, the selection of diagnostic criteria for BPD, the selection of respiratory support mode in treatment and the use of glucocorticoids are still problems that clinicians are confused and concerned about. This manuscript compared the different diagnostic criteria of BPD, which are all commonly used in the last decade. In addition, we discussed respiratory support management and glucocorticoid use in the prevention and treatment of BPD in neonates.
Fang LI , Liting LIU . Concerns about diagnosis and treatment of bronchopulmonary dysplasia[J]. Journal of Clinical Pediatrics, 2022 , 40(6) : 413 -419 . DOI: 10.12372/jcp.2022.22e0333
| [1] | Stoll BJ, Hansen NI, Bell EF, et al. Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012 [J]. JAMA, 2015, 314(10): 1039-1051. |
| [2] | Jobe AH, Bancalari E. Bronchopulmonary dysplasia[J]. Am J Respir Crit Care Med, 2001, 163(7): 1723-1729. |
| [3] | Higgins RD, Jobe AH, Koso-Thomas M, et al. Bronchopulmonary Dysplasia: Executive Summary of a Workshop[J]. J Pediatr, 2018, 197: 300-308. |
| [4] | Jensen EA, Dysart K, Gantz MG, et al. The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach[J]. Am J Respir Crit Care Med, 2019, 200(6): 751-759. |
| [5] | Han YS, Kim SH, Sung TJ. Impact of the definition of bronchopulmonary dysplasia on neurodevelopmental outcomes[J]. Sci Rep, 2021, 11(1): 22589. |
| [6] | 王陈红, 沈晓霞, 陈鸣艳, 等. 不同诊断标准下早产儿支气管肺发育不良诊断及预后分析[J]. 中华儿科杂志, 2020, 58(5): 381-386. |
| [7] | Vyas-Read S, Logan JW, Cuna AC, et al. A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children's Hospitals Neonatal Consortium Severe BPD Group[J]. J Perinatol, 2022, 42(1): 58-64. |
| [8] | Isayama T, Lee SK, Yang J, et al. Revisiting the Definition of Bronchopulmonary Dysplasia: Effect of Changing Panoply of Respiratory Support for Preterm Neonates[J]. JAMA Pediatr, 2017, 171(3): 271-279. |
| [9] | Zhang ZQ, Huang XM, Lu H. Early biomarkers as predictors for bronchopulmonary dysplasia in preterm infants: a systematic review[J]. Eur J Pediatr, 2014, 173(1): 15-23. |
| [10] | Yang Y, Li J, Mao J. Early diagnostic value of C-reactive protein as an inflammatory marker for moderate-to-severe bronchopulmonary dysplasia in premature infants with birth weight less than 1500 g[J]. Int Immunopharmacol, 2022, 103: 108462. |
| [11] | Ahmed S, Odumade OA, van Zalm P, et al. Urine Proteomics for Noninvasive Monitoring of Biomarkers in Bronchopulmonary Dysplasia[J]. Neonatology, 2022, 119(2): 193-203. |
| [12] | Schmidt AR, Ramamoorthy C. Bronchopulmonary dysplasia[J]. Paediatr Anaesth, 2022, 32(2): 174-180. |
| [13] | 杜立中, 早产儿支气管肺发育不良临床管理专家共识[J]. 中华儿科杂志, 2020(5): 358-365. |
| [14] | Gilfillan M, Bhandari A, Bhandari V. Diagnosis and management of bronchopulmonary dysplasia[J]. BMJ, 2021, 375: n1974. |
| [15] | González-Pacheco N, Sánchez-Luna M, Chimenti-Camacho P, et al. Use of very low tidal volumes during high-frequency ventilation reduces ventilator lung injury[J]. J Perinatol, 2019, 39(5): 730-736. |
| [16] | Ramos-Navarro C, González-Pacheco N, Rodríguez-Sánchez de la Blanca A, et al. Effect of a new respiratory care bundle on bronchopulmonary dysplasia in preterm neonates[J]. Eur J Pediat, 2020, 179(12): 1833-1842. |
| [17] | Sánchez-Luna M, González-Pacheco N, Belik J, et al. New Ventilator Strategies: High-Frequency Oscillatory Ventilation Combined with Volume Guarantee[J]. Am J Perinatol, 2018, 35(6): 545-548. |
| [18] | Enomoto M, Keszler M, Sakuma M, et al. Effect of Volume Guarantee in Preterm Infants on High-Frequency Oscillatory Ventilation: A Pilot Study[J]. Am J Perinatol, 2017, 34(1): 26-30. |
| [19] | Shetty S, Hunt K, Peacock J, et al. Crossover study of assist control ventilation and neurally adjusted ventilatory assist[J]. Eur J Pediatr, 2017, 176(4): 509-513. |
| [20] | Makker K, Cortez J, Jha K, et al. Comparison of extubation success using noninvasive positive pressure ventilation (NIPPV) versus noninvasive neurally adjusted ventilatory assist (NI-NAVA)[J]. J Perinatol, 2020, 40(8): 1202-1210. |
| [21] | McKinney RL, Keszler M, Truog WE, et al. Bronchopulmonary Dysplasia Collaborative. Multicenter Experience with Neurally Adjusted Ventilatory Assist in Infants with Severe Bronchopulmonary Dysplasia[J]. Am J Perinatol, 2021, 38(S 01): e162-e166. |
| [22] | Barrington KJ. The adverse neuro-developmental effects of postnatal steroids in the preterm infant: a systematic review of RCTs[J]. BMC Pediatr, 2001, 1:1. |
| [23] | Doyle LW, Cheong JL, Hay S, et al. Late (≥ 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants[J]. Cochrane Database Syst Rev. 2021, 11(11): CD001145. |
| [24] | Doyle LW, Davis PG, Morley CJ, et al. Low-dose dexamethasone facilitates extubation among chronically ventilator-dependent infants: a multicenter, international, randomized, controlled trial[J]. Pediatrics, 2006, 117(1): 75-83. |
| [25] | Cuna A, Lagatta JM, Savani RC, et al. Association of time of first corticosteroid treatment with bronchopulmonary dysplasia in preterm infants[J]. Pediatr Pulmonol, 2021, 56(10): 3283-3292. |
| [26] | Ramaswamy VV, Bandyopadhyay T, Nanda D, et al. Assessment of Postnatal Corticosteroids for the Prevention of Bronchopulmonary Dysplasia in Preterm Neonates: A Systematic Review and Network Meta-analysis[J]. JAMA Pediatr, 2021, 175(6): e206826. |
| [27] | Lemyre B, Dunn M, Thebaud B. Postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia in preterm infants[J]. Paediatr Child Health. 2020, 25(5): 322-331. |
| [28] | Doyle LW, Cheong JL, Hay S, et al. Early (<7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants[J]. Cochrane Database Syst Rev, 2021, 10(10): CD001146. |
| [29] | Onland W, Cools F, Kroon A, et al. Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial[J]. JAMA, 2019, 321(4): 354-363. |
| [30] | Watterberg KL, Walsh MC, Li L, et al. Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia[J]. N Engl J Med, 2022, 386(12): 1121-1131. |
| [31] | Bassler D, Shinwell ES, Hallman M, et al. Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia[J]. N Engl J Med, 2018, 378(2): 148-157. |
| [32] | Duijts L, van Meel ER, Moschino L, et al. European Respiratory Society guideline on long-term management of children with bronchopulmonary dysplasia[J]. Eur Respir J, 2020, 55(1): 1900788. |
| [33] | Szabó H, Baraldi E, Colin AA. Corticosteroids in the prevention and treatment of infants with bronchopulmonary dysplasia: Part II. Inhaled corticosteroids alone or in combination with surfactants[J]. Pediatr Pulmonol, 2022, 57(4): 787-795. |
| [34] | Volarevic V, Markovic BS, Gazdic M, et al. Ethical and Safety Issues of Stem Cell-Based Therapy[J]. Int J Med Sci, 2018, 15(1): 36-45. |
| [35] | Tong Y, Zuo J, Yue D. Application Prospects of Mesenchymal Stem Cell Therapy for Bronchopulmonary Dysplasia and the Challenges Encountered[J]. Biomed Res Int. 2021, 2021: 9983664. |
| [36] | Tieu A, Hu K, Gnyra C, et al. Mesenchymal stromal cell extracellular vesicles as therapy for acute and chronic respiratory diseases: a meta-analysis[J]. J Extracell Vesicles, 2021, 10(12): e12141. |
/
| 〈 |
|
〉 |
