Literature Review

Application of biological agents in idiopathic nephrotic syndrome

  • Qianhui Reviewer: WANG ,
  • Fei LIU ,
  • Haidong FU ,
  • Jianhua Reviser: MAO
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  • Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310006, Zhejiang, China

Received date: 2021-10-15

  Online published: 2022-10-12

Abstract

Idiopathic nephrotic syndrome (INS) is the commonest glomerular disease in children. Refractory nephrotic syndromes such as frequent relapses, steroid dependence and steroid resistance are still the current difficulties in clinical INS treatment. In recent years, it has been reported that rituximab (RTX) and other biological agents have been used in the treatment of refractory nephrotic syndrome and have achieved good results. This article reviews the application progress of RTX and other biological agents in INS.

Cite this article

Qianhui Reviewer: WANG , Fei LIU , Haidong FU , Jianhua Reviser: MAO . Application of biological agents in idiopathic nephrotic syndrome[J]. Journal of Clinical Pediatrics, 2022 , 40(10) : 787 -794 . DOI: 10.12372/jcp.2022.21e1440

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