Journal of Clinical Pediatrics >
Effect of SARS-CoV-2 infection on pulmonary function in children with asthma
Received date: 2023-03-13
Online published: 2023-05-10
The pandemic of COVID-19 raises new challenges in the management of pediatric asthma. We analyzed airway injury in children with asthma from molecular mechanism to pathological alterations and explored the effect of SARS-CoV-2 on pulmonary function, which will inform clinicians in the diagnosis and management of childhood asthma in the context of the new coronavirus epidemic.
Key words: respiratory virus; SARS-CoV-2; lung function; bronchial asthma; child
Jinrong WANG , Yu MIAO , Guangzeng MA , Luofei CAO . Effect of SARS-CoV-2 infection on pulmonary function in children with asthma[J]. Journal of Clinical Pediatrics, 2023 , 41(5) : 333 -338 . DOI: 10.12372/jcp.2022.23e0163
[1] | World Health Organization. WHO Coronavirus (COVID-19)[EB/OL]. [2022-02-25]. https://covid19.who.int. |
[2] | No authors listed. The global asthma report 2022[J]. Int J Tuberc Lung Dis, 2022, 26(1): 1-104. |
[3] | Campos C, Prokopich S, Loewen H, et al. Long-term effect of COVID-19 on lung imaging and function, cardiorespiratory symptoms, fatigue, exercise capacity, and functional capacity in children and adolescents: a systematic review and meta-analysis[J]. Healthcare (Basel), 2022, 10(12): 2492. |
[4] | Seibold MA, Moore CM, Everman JL, et al. Risk factors for SARS-CoV-2 infection and transmission in households with children with asthma and allergy: a prospective surveillance study[J]. J Allergy Clin Immunol, 2022, 150(2): 302-311. |
[5] | Kompaniyets L, Agathis NT, Nelson JM, et al. Underlying medical conditions associated with severe COVID-19 illness among children[J]. JAMA Netw Open, 2021, 4(6): e2111182. |
[6] | Shi T, Pan J, Katikireddi SV, et al. Risk of COVID-19 hospital admission among children aged 5-17 years with asthma in Scotland: a national incident cohort study[J]. Lancet Respir Med, 2022, 10: 191-198. |
[7] | Chiang CY, Ellwood P, Ellwood E, et al. Infection with SARS-CoV-2 among children with asthma: evidence from Global Asthma Network[J]. Pediatr Allergy Immunol, 2022, 33(1): e13709. |
[8] | Pivniouk V, Pivniouk O, DeVries A, et al. The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression[J]. J Allergy Clin Immunol, 2022, 149(3): 923-933.. |
[9] | Tay MZ, Poh CM, Rénia L, et al. The trinity of COVID-19: immunity, inflammation and intervention[J]. Nat Rev Immunol, 2020, 20(6): 363-374. |
[10] | Vora SM, Lieberman J, Wu H. Inflammasome activation at the crux of severe COVID-19[J]. Nat Rev Immunol, 2021, 21(11): 694-703. |
[11] | Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J]. Lancet (London, England), 2020, 395(10223): 497-506. |
[12] | Shoenfeld Y. Corona (COVID-19) time musings: our involvement in COVID-19 pathogenesis, diagnosis, treatment and vaccine planning[J]. Autoimmun Rev, 2020, 19(6): 102538. |
[13] | Zhao L, Zhang YP, Yang X, et al. Eosinopenia is associated with greater severity in patients with coronavirus disease 2019[J]. Allergy, 2021, 76: 562-564. |
[14] | Crook H, Raza S, Nowell J, et al. Long covid-mechanisms, risk factors, and management[J]. BMJ, 2021, 374: n1648. |
[15] | Cui S, Chen S, Li X, et al. Prevalence of venous throm-boembolism in patients with severe novel coronavirus pneumonia[J]. J Thromb Haemost, 2020, 18(6): 1421-1424. |
[16] | Torres-Castro R, Vasconcello-Castillo L, Alsina-Restoy X, et al. Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis[J]. Pulmonology, 2021, 27: 328-337. |
[17] | ?ztürk GK, Beken B, Do?an S, et al. Pulmonary function tests in the follow-up of children with COVID-19[J]. Eur J Pediatr, 2022, 181: 2839-2847. |
[18] | Soyak Aytekin E, Sahiner UM, Tuten Dal S, et al. Obesity is a risk factor for decrease in lung function after COVID-19 infection in children with asthma[J]. Pediatr Pulmonol, 2022, 57: 1668-1676. |
[19] | Choudhary S, Sharma K, Silakari O. The interplay between inflammatory pathways and COVID-19: a critical review on pathogenesis and therapeutic options[J]. Microb Pathog, 2021, 150: 104673. |
[20] | D'Agnillo F, Walters KA, Xiao Y, et al. Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19[J]. Sci Transl Med, 2021, 13: eabj7790. |
[21] | Du X, Yang Y, Yang Mg et al. ITGB4 deficiency induces mucus hypersecretion by upregulating MUC5AC in RSV-infected airway epithelial cells[J]. Int J Biol Sci, 2022, 18: 349-359. |
[22] | Sajuthi SP, DeFord P, Li Y, et al. Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium[J]. Nat Commun, 2020, 11(1): 5139. |
[23] | Postma DS, Brightling C, Baldi S, et al. Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study[J]. Lancet Respir Med, 2019, 7(5): 402-416. |
[24] | Ashkenazi-Hoffnung L, Shmueli E, Ehrlich S, et al. Long COVID in children: observations from a designated pediatric clinic[J]. Pediatr Infect Dis J, 2021, 40: e509-e511. |
[25] | Maniscalco M, Ambrosino P, Fuschillo S, et al. Bronchodilator reversibility testing in post-COVID-19 patients undergoing pulmonary rehabilitation[J]. Respir Med, 2021, 182: 106401. |
[26] | Xu Z, Shi L, Wang Y, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome[J]. Lancet Respir Med, 2020, 8(4): 420-422. |
[27] | 国家儿童医学中心, 首都医科大学附属北京儿童医院新型冠状病毒感染重症救治专家组, 北京儿童新型冠状病毒感染医疗救治市级专家组. 儿童新型冠状病毒Omicron变异株感染重症早期识别和诊治建议[J]. 中华儿科杂志, 2023, 61(3): 199-202. |
[28] | Faverio P, Luppi F, Rebora P, et al. Six-month pulmonary impairment after severe COVID-19: a prospective, multicentre follow-up study[J]. Respiration, 2021, 100: 1078-1087. |
[29] | Xu C, Ma M, Yi Y, et al. Clinical features and high-resolution chest computerized tomography findings of children infected by the B.1.617.2 variant of coronavirus disease 2019[J]. Ann Med, 2022, 54(1): 2391-2401. |
[30] | Long ME, Mallampalli RK, Horowitz JC. Pathogenesis of pneumonia and acute lung injury[J]. Clin Sci (Lond), 2022, 136(10): 747-769. |
[31] | Heiss R, Tan L, Schmidt S, et al. Pulmonary dysfunction after pediatric COVID-19[J]. Radiology, 2023, 306(3): e221250. |
[32] | Camporota L, Cronin JN, Busana M, et al. Pathophysiology of coronavirus-19 disease acute lung injury[J]. Curr Opin Crit Care e, 2022, 28(1): 9-16. |
[33] | Xiao C, Puddicombe SM, Field S, et al. Defective epithelial barrier function in asthma[J]. J Allergy Clin Immunol, 2011, 128(3): 549-556. |
[34] | Bajbouj K, Ramakrishnan RK, Hamid Q. Role of matrix metalloproteinases in angiogenesis and its implications in asthma[J]. J Immunol Res, 2021: 6645072. |
[35] | Lee KS, Min KH, Kim SR, et al. Vascular endothelial growth factor modulates matrix metalloproteinase-9 expression in asthma[J]. Am J Respir Crit Care Med, 2006, 174(2): 161-170. |
[36] | Lucas C, Wong P, Klein J, et al. Longitudinal analyses reveal immunological misfiring in severe COVID-19[J]. Nature, 2020, 584(7821): 463-469. |
[37] | Pathinayake PS, Awatade NT, Wark PAB. Type 2 immunity and its impact on COVID-19 infection in the airways[J]. Viruses, 2023, 15(2): 402. |
[38] | Roberts LM, Jessop F, Wehrly TD, et al. CuttinG EDGE: LUNG-RESident T cells elicited by SARS-CoV-2 do not mediate protection against secondary infection[J]. J Immunol, 2021, 207(10): 2399-404. |
[39] | Rahimi RA, Nepal K, Cetinbas M, et al. Distinct functions of tissue-resident and circulating memory Th2 cells in allergic airway disease[J]. J Exp Med, 2020, 217(9) : e20190865. |
[40] | May BC, Gallivan KH. Levocetirizine and montelukast in the COVID-19 treatment paradigm[J]. Int Immu-nopharmacol, 2022, 103: 108412. |
[41] | Mera-Cordero F, Bonet-Monne S, Almeda-Ortega J, et al. Double-blind placebo-controlled randomized clinical trial to assess the efficacy of montelukast in mild to moderate respiratory symptoms of patients with long COVID: E-SPERANZA COVID Project study protocol[J]. Trials, 2022, 23(1): 19. |
[42] | Zhang L, Wang X, Huang Y, et al. Pediatric asthma situation in Chengdu, China, during the COVID-19 pandemic: an observational study[J]. J Asthma Allergy, 2021, 14: 829-838. |
[43] | Borg Bm, Osadnik C, Adam K, et al. Pulmonary function testing during SARS-CoV-2: An ANZSRS/TSANZ position statement[J]. Respirology, 2022, 27(9): 688-719. |
[44] | Franczuk M, Przyby?owski T, Czajkowska-Malinowska M, et al. Spirometry during the SARS-CoV-2 pandemic. Guidelines and practical advice from the expert panel of Respiratory Physiopathology Assembly of Polish Respiratory Society[J]. Adv Respir Med, 2020, 88(6): 640-650. |
/
〈 |
|
〉 |