Objective To analyze the clinical rationality of pulmonary function parameters associated with obstructive ventilation dysfunction in children. Methods Children aged 6-18 years who attended the respiratory department and completed pulmonary function tests from January to December 2021 were selected and grouped at an age interval of one year. The relevant lung function parameters such as forced vital capacity (FVC), maximum vital capacity (VC_max), forced expiratory volume in the first second (FEV₁), FEV₁/FVC, FEV₁/VC_max were detected. The clinical consistency between measured and measured/predicted value of FEV₁/FVC, measured and measured/predicted value of FEV₁/VC_max, respectively, in the interpretation of obstructive lesions was compared. Results A total of 7025 children were enrolled, including 4543 males and 2482 females with median age of (8.6±2.5) years old, with the largest number of children aged 6-10 years old. Except for 10-11 and 11-12 age group, the volume correlation parameters FVC, VC_max and FEV₁ were greater in males than in females, and their absolute values increased with the increase of age. There was a slight difference between VC_max and FVC in all age groups, and VC_max was slightly higher than FVC. The measured and predicted values of FEV₁/FVC in females were higher than those in males except 15-16 and 16-17 age group. The measured and predicted values of FEV₁/VC_max for females were higher than those for males except for 13-14 and 16-17 age group. When the measured value of FEV₁/FVC < 80% and the measured/predicted value of FEV₁/FVC < 92%, the interpretation inconsistency rate is 6.8%, and the interpretation inconsistency rate between the measured value of FEV₁/FVC and the measured value of FEV₁/VC_max is 5.0%. Finally, the ideal FEV₁/VC_max measured/predicted value is 93.9%. Conclusions The measured/predicted value of FEV₁/VC_max <93.9% can be used as a clinical reference standard for the interpretation of obstructive ventilation dysfunction in children.