Journal of Clinical Pediatrics >
The role of early regular use of emollients in the prevention and treatment of infantile atopic dermatitis
Received date: 2023-11-28
Online published: 2024-09-04
Impaired epidermal barrier function plays a pivotal role in the pathogenesis of atopic dermatitis (AD). Emollients can fortify the skin barrier, diminish transepidermal water loss, and maintain stratum corneum hydration. AD is closely associated with comorbidities such as food allergies, allergic rhinitis, and allergic asthma. Implementing effective preventive measures in the early stages of AD can alleviate the economic burden on families and society. This review explores the relationship between AD and skin barrier and allergic diseases, as well as the application of emollients in the prevention of AD, and discusses whether regular use of emollients in early neonates can effectively prevent the occurrence of atopic dermatitis and reduce the risk of allergic diseases.
Key words： atopic dermatitis; emollient; epidermal barrier; allergic disease
Chuanyi Reviewer: TANG , Zhirong Reviser: YAO . The role of early regular use of emollients in the prevention and treatment of infantile atopic dermatitis[J]. Journal of Clinical Pediatrics, 2024 , 42(9) : 817 -821 . DOI: 10.12372/jcp.2024.23e1132
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