Journal of Clinical Pediatrics >
Prognostic factors analysis of adenovirus type 3 pneumonia in children
Received date: 2024-12-31
Accepted date: 2025-07-10
Online published: 2025-08-27
Objective To analyze the clinical characteristics of children with respiratory adenovirus type 3 infection and the influencing factors of adenovirus type 3 pneumonia in children. Methods A retrospective analysis was conducted on the clinical data of children with respiratory adenovirus type 3 infection admitted to the hospital's infectious disease department from January to October 2024. The possible influencing factors of the occurrence of adenovirus type 3 pneumonia were analyzed through multivariate logistic regression. Results A total of 159 children (87 boys and 72 girls) with adenovirus type 3 infection were included, with a median age of 59.0 (41.0-81.0) months. Multivariate logistic regression analysis showed that tonsillar exudation and elevated CRP level were independent protective factors for adenovirus type 3 pneumonia in children (P<0.05), while cough, expectoration and elevated D-dimer level were independent risk factors for adenovirus type 3 pneumonia (P<0.05). Conclusions In the early course of respiratory adenovirus type 3 infection in children, tonsillar exudation may indicate mild pulmonary symptoms, suggesting that the tonsils may play an important defensive role in the immune response of acute adenovirus infection.
Key words： adenovirus type 3; pneumonia; tonsillar exudation; child
XIANG Linjuan , CHEN Xuexin , JIA Yanhui , WU Yuhang , CONG Xin , LI Wei , CHEN Yingying , CHEN Sun , HUANG Lisu . Prognostic factors analysis of adenovirus type 3 pneumonia in children[J]. Journal of Clinical Pediatrics, 2025 , 43(9) : 686 -691 . DOI: 10.12372/jcp.2025.24e1412
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