Journal of Clinical Pediatrics >
Air-conduction tone burst auditory brainstem response thresholds in infants and young children with otitis media with effusion
Received date: 2025-07-09
Accepted date: 2025-09-10
Online published: 2025-11-28
Objective To analyze the air-conduction click (c-ABR) and tone burst auditory brainstem response (Tb-ABR) thresholds in infants and young children with otitis media with effusion (OME) and explore the clinical significance of air-conduction Tb-ABR thresholds in frequency-specific hearing assessment for OME infants and young children. Methods A retrospective analysis was conducted on the ABR threshold test results of OME infants and young children aged 0~24 months and normal control infants from January 2018 to December 2022. The air-conduction click, Tb-500 Hz, Tb-1000 Hz, Tb-2000 Hz, and Tb-4000 Hz ABR thresholds were compared between the two groups. The correlation between c-ABR and Tb-ABR thresholds within the OME group was analyzed. Results The OME group consisted of 43 patients (28 boys and 15 girls), with a median age of 8 (3-14) months. The following testing was completed: air-conduction click for 43 cases (60 ears), Tb-500 Hz for 32 cases (45 ears), Tb-1000 Hz for 27 cases (39 ears), Tb-2000 Hz for 11 cases (17 ears), and Tb-4000 Hz for 11 cases (17 ears). The control group included 21 patients (10 boys and 11 girls), with a median age of 6 (4-8.25) months. The following tests were completed for the control group: air-conduction click, Tb-500 Hz, Tb-1000 Hz, Tb-2000 Hz, and Tb-4000 Hz for 21 cases (42 ears). The air-conduction click and Tb-ABR thresholds at Tb-500 Hz, Tb-1000 Hz, Tb-2000 Hz, and Tb-4000 Hz in the OME group were all significantly higher than those in the normal control group (P<0.01). In the OME group, the air-conduction c-ABR threshold was lower than the thresholds for Tb-ABR at all four frequencies (P<0.05). A positive correlation was found between the thresholds at different frequencies (P<0.05), and the correlation coefficient between Tb-2000 Hz and Tb-4000 Hz was 0.925. Conclusions Infants and young children with OME may experience hearing loss across a range of frequencies, from low to high. Compared to air-conduction c-ABR, Tb-ABR thresholds provide more information about frequency-specific hearing. In clinical settings with limited testing time, Tb-2000 Hz or Tb-4000 Hz might be selected for threshold testing, in addition to 500 Hz and 1000 Hz.
WANG Wei , WANG Lu , SHEN Jiali , MA Xiaobao , HE Kuan , SONG Jiayue , CHEN Jianyong , YANG Jun , JIN Yulian . Air-conduction tone burst auditory brainstem response thresholds in infants and young children with otitis media with effusion[J]. Journal of Clinical Pediatrics, 2025 , 43(12) : 902 -907 . DOI: 10.12372/jcp.2025.25e0793
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