Pathological typing and clinical features in 70 cases of pediatric interstitial pneumonia

  • LI Min ,
  • WEI Zehong ,
  • YAN Xin ,
  • SONG Tao ,
  • LI Jianbo ,
  • TANG Renkuan ,
  • ZHAO Minzhu ,
  • DONG Yuan ,
  • LIU Yunzhi
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  • 1. Department of Forensic Medicine, Chongqing Medical University, Chongqing 400016, China; 2.Criminal Police Detachment of Yubei District Branch Bureau , Chongqing Public Security Bureau, Chongqing 400030, China; 3.Department of pediatrics, Beijing Children's Hospital Affiliated to Capital University of Medical Sciences, Beijing 100045, China

Received date: 2014-08-15

  Online published: 2014-08-15

Abstract

Objective To better understand pathological types of pediatric interstitial pneumonia and improve clinical diagnosis by analyzing the clinical records and pathological typing of interstitial pneumonia. Methods 70 cases of children diagnosed as interstitial pneumonia by autopsy were retrospectively analyzed. Results The number of males was more than that of females. There was a significant predominance of infants less than 2 years. The clinical features include acute onset, rapid development, short duration and atypical clinical manifestations. Most patients had poor prognosis and curative effect with general therapies. Twelve cases had dubious etiology. Pathologic types of 58 cases with unclear etiology were diffuse alveolar damage type (DAD type, 38/58), desquamative interstitial pneumonia type (DIP type, 5/58), lymphoid interstitial pneumonia type (LIP type, 3/58), DAD type complicating DIP type (6/58), DAD type complicating LIP type (2/58), DAD type complicating respiratory bronchiolotitis-associated interstitial lung disease type (RB-ILD type, 3/58), DIP type complicating LIP type (1/58). Conclusions The confirmed diagnosis rate was relatively low for pediatric interstitial pneumonia. Postmortem examination was helpful for diagnosis and improving clinical diagnosis and pathological typing.

Cite this article

LI Min , WEI Zehong , YAN Xin , SONG Tao , LI Jianbo , TANG Renkuan , ZHAO Minzhu , DONG Yuan , LIU Yunzhi . Pathological typing and clinical features in 70 cases of pediatric interstitial pneumonia[J]. Journal of Clinical Pediatrics, 2014 , 32(8) : 727 . DOI: 10.3969 j.issn.1000-3606.2014.08.008

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