An update on pathogenesis and treatment of Glanzmann thrombasthenia

  • GAO Min
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  • Hematology Department of Children’s Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing,Chongqing 400014, China

Received date: 2015-05-15

  Online published: 2015-05-15

Abstract

 Glanzmann thrombasthenia (GT) is an inherited disease of platelet function disorders characterized by mucocutaneous bleeding due to platelets failed to aggregate in response to physiologic stimuli. GT is a rare inherited disease and caused by quantitative or qualitative deficiencies of an integrin receptor GP Ⅱb/Ⅲa for adhesive proteins. There is no unified treatment strategy available so far for GT. This review summarizes the update of pathogenesis treatment progresses in GT.

Cite this article

GAO Min . An update on pathogenesis and treatment of Glanzmann thrombasthenia[J]. Journal of Clinical Pediatrics, 2015 , 33(5) : 486 . DOI: 10.3969 j.issn.1000-3606.2015.05.022

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