The progress of podocyte autophagy and PI3K/Akt signaling pathway 

  • YU Li ,
  • GE Lin
Expand
  • Department of Pediatrics, Guangzhou Medical University Affiliated Guangzhou First People's Hospital, Guangzhou 510180, Guangdong, China

Received date: 2015-06-15

  Online published: 2015-06-15

Abstract

Autophagy is the process that cells degradate the damaged organelles and the macromolecules by lysosomes. It is a phenomenon of life which is widely existed in nature and plays an important role in maintaining the stability of cellular structure. Current studies showed that the PI3K/Akt signaling pathway, which involved in multiple physiological and pathological processes, is one of the important signaling pathways of autophagy. Recent studies found that the levels of podocyte autophagy and the podocyte diseases have close relationship with PI3K/Akt signaling pathway. In this article, the relationship between autophagy and the PI3K/Akt pathway will be reviewed.

Cite this article

YU Li , GE Lin . The progress of podocyte autophagy and PI3K/Akt signaling pathway [J]. Journal of Clinical Pediatrics, 2015 , 33(6) : 501 . DOI: 10.3969j.issn.1000-3606.2015.06.001

Outlines

/