One case report of neonatal onset Crohn disease

  •  LIU Xiaojing ,
  • CHEN Yongxing ,
  • WEI Haiyan ,
  • YANG Wei ,
  • LI Chunzhi ,
  • ZHOU Xihong ,
  • GAO Jing
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  • 1. Department of Endocrine and Genetic Metabolism; 2. Department of Gastroenterology, Zhengzhou Children’s Hospital, Zhengzhou 450052, Henan, China

Received date: 2015-09-15

  Online published: 2015-09-15

Abstract

Objective To investigate the diagnosis and treatment of Crohn disease in neonates. Methods  The clinical data of one case of neonatal onset Crohn disease were retrospectively analyzed. Results  Male infant had intermittent fever, recurrent oral ulcers, skin impetigo and intermittent diarrhea with increased WBC counts from five days after birth. He had been diagnosed as sepsis, bacterial enteritis, Behcet's disease, immunodeficiency disease, nutritional anemia, milk intolerance, and inflammatory bowel disease. Finally he was diagnosed as Crohn disease by rectal mucosa pathology and postoperative bowel pathology. He died of intestinal perforation on 8 months. Conclusions  The infants who have recurrent oral ulcers, skin impetigo, perianal ulcers and fever from neonatal should undergo colonoscopy for the diagnosis.

Cite this article

 LIU Xiaojing , CHEN Yongxing , WEI Haiyan , YANG Wei , LI Chunzhi , ZHOU Xihong , GAO Jing . One case report of neonatal onset Crohn disease[J]. Journal of Clinical Pediatrics, 2015 , 33(9) : 776 . DOI: 10.3969 j.issn.1000-3606.2015.09.004

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