One case report of autoantibody-associated congenital heart block

  • FENG Zongtai ,
  • YANG Xiaolu ,
  • WANG Sannan ,
  • YANG Zuming ,
  • CAI Yan
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  • Department of Neonates, Suzhou Municipal Hospital of Nanjing Medical University, Suzhou 215002, Jiangsu, china

Received date: 2015-10-15

  Online published: 2015-10-15

Abstract

Objective To explore the pathogenesis, clinical manifestations, diagnosis, and treatment of autoantibody-associated congenital heart block. Methods The clinical data of one child with autoantibody-associated congenital heart block was retrospectively analyzed. Results In 24 week gestation, fetal bradycardia had been found by routine fetal echocardiography. After birth, the anti-SSA/Ro antibodies and anti-SSB/La antibodies were positive in both infant and her mother. The diagnosis of autoantibody-associated congenital heart block was confirmed. Intravenous immunoglobulin at 1 g/kg was administrated. At 6 months follow-up, the electrocardiogram suggested type I second degree atrioventricular block. Conclusion In the fetus or neonates found to have bradycardia and excluded the cardiac structural abnormalities, the autoimmune antibody should been tested and early intervention should been promoted.

Cite this article

FENG Zongtai , YANG Xiaolu , WANG Sannan , YANG Zuming , CAI Yan . One case report of autoantibody-associated congenital heart block[J]. Journal of Clinical Pediatrics, 2015 , 33(10) : 880 . DOI: 10.3969 j.issn.1000-3606.2015.10.010

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