Clinical analysis of eight cases of essential thrombocythemia in children

  • LIANG Hui
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  • 1. Chongming Branch, Xinhua Hospital Affiliate to Shanghai Jiaotong University School of Medicine, Shanghai 202150,China;2. Department of Hematology, Xinhua Hospital Affiliate to Shanghai Jiaotong University School of Medicine,Shanghai 200092,China

Received date: 2015-11-15

  Online published: 2015-11-15

Abstract

Objective To explore the diagnosis and treatment of essential thrombocythemia in children. Methods The clinical data from 8 children with essential thrombocythemia were retrospectively analyzed. Results From January 2010 to June 2015, there were 8 children diagnosed essential thrombocythemia in clinic. One child was only 10 months old. Among them, 6 cases had JAK2V617F mutation, 2 cases had no mutation. All children were treated with hydroxyurea or interferon-α, and achieve remission. Conclusion Essential thrombocythemia is a rare disease in childhood with a growing trend. More children with essential thrombocythemia should be enrolled for comparison of clinical manifestations and prognosis between JAK2V617F mutation positive and negative cases.

Cite this article

LIANG Hui . Clinical analysis of eight cases of essential thrombocythemia in children[J]. Journal of Clinical Pediatrics, 2015 , 33(11) : 979 . DOI: 10.3969 j.issn.1000-3606.2015.11.015

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