The progress of the mechanism on brain protection of remote ischemic preconditioning

  • LU Fangfang ,
  • WANG Wei
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  • Department of Pediatric Thoracic and Cardiovascular Surgery, Shanghai Children’s Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200127,China

Received date: 2016-08-15

  Online published: 2016-08-15

Abstract

In recent years, remote ischemic preconditioning is found as a novel way to protect the brain, which may be achieved  through nerve pathways, humoral factors or nerve-humoral interaction. The molecular mechanisms for the protection might be related  to mitochondria ATP-sensitive potassium channel, mitogen-activated protection kinase, mammalian target of rapamycin, including  nitric oxide synthase and cannabinoid receptors. The aim of this review is to explain the mechanism of action of remote ischemic  preconditioning on brain protection, as well as the possible direction of clinical application.

Cite this article

LU Fangfang , WANG Wei . The progress of the mechanism on brain protection of remote ischemic preconditioning[J]. Journal of Clinical Pediatrics, 2016 , 34(8) : 634 . DOI: 10.3969/j.issn.1000-3606.2016.08.017

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