Progress on roles of type 2 innate lymphoid cells in the pathogenesis of asthma

  • JIANG Qin
Expand
  • 1. Shanghai Jiao Tong University of Medicine, Shanghai 200233, China; 2.Department of Pediatrics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233 , China

Received date: 2017-02-15

  Online published: 2017-02-15

Abstract

Type 2 innate lymphoid cell (ILC2) is a new member of the innate lymphoid cell family discovered recently. After being exposed to antigens, ILC2 was activated by epithelial cell-derived cytokines, lipid mediators and TNF family member TL1A to promote structural and immune cell responses in the airways. These cells are critical components of the innate immune response involved in the pathogenesis of asthma. This paper summarizes the progress on the roles of type 2 innate lymphoid cells in the pathogenesis of asthma.

Cite this article

JIANG Qin . Progress on roles of type 2 innate lymphoid cells in the pathogenesis of asthma[J]. Journal of Clinical Pediatrics, 2017 , 35(2) : 148 . DOI: 10.3969/j.issn.1000-3606.2017.02.017

Outlines

/