延迟脐带结扎对足月儿影响的meta分析

临床儿科杂志 ›› 2014, Vol. 32 ›› Issue (3): 278-283.

延迟脐带结扎对足月儿影响的meta分析

余章斌，韩树萍，沙莉，董小玥，陈玉林，邱玉芳

南京医科大学附属南京妇幼保健院儿科（江苏南京　210004）

收稿日期:2013-09-21 出版日期:2014-03-15 发布日期:2014-03-15

Effect of delayed cord clamping in term infants: a meta-analysis

YU Zhangbin, HAN Shuping, SHA Li, DONG Xiaoyue, CHEN Yulin, QIU Yufang

(Department of Pediatrics, Nanjing Maternal and Child Health Hospital Affiliated to Nanjing Medical University, Nanjing 210004, Jiangsu, China)

Received:2013-09-21 Online:2014-03-15 Published:2014-03-15

摘要/Abstract

摘要：

　目的　评价延迟脐带结扎（DCC）对足月儿的影响。方法　检索Cochrane 图书馆、PubMed、EMBASE、中国知网、维普、万方数据库，检索时间均从1970年1月起至2013年4月；对纳入文献进行质量评价，并采用RevMan 5.1.0软件进行meta分析。结果　共纳入10篇文献，总样本量为1 623例。Meta分析结果显示，与立即结扎脐带相比，DCC可以明显提高足月儿出生后血红蛋白的水平（MD=2.19，95%CI：0.36~4.02），对足月儿6个月内血红蛋白的水平没有影响（MD=0.29，95%CI：-0.17~0.75），对足月儿6个月内贫血的发生率没有影响（RR=0.71，95%CI：0.45~1.12），但增加足月儿出生后红细胞增多症的发生率（RR=2.87，95%CI：1.24~6.62），对于高胆红素血症光疗没有影响（RR=2.46，95%CI：0.93~6.52）。结论　DCC能改善足月儿出生后的血红蛋白水平；但关于合适的延长时间没有研究进行评价，需要进一步开展高质量、大样本随机对照试验评价合适的DCC的时间。

余章斌，韩树萍，沙莉，董小玥，陈玉林，邱玉芳. 延迟脐带结扎对足月儿影响的meta分析[J]. 临床儿科杂志, 2014, 32(3): 278-283.

YU Zhangbin,HAN Shuping,SHA Li,DONG Xiaoyue,CHEN Yulin,QIU Yufang . Effect of delayed cord clamping in term infants: a meta-analysis[J]. , 2014, 32(3): 278-283.

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