非孤立性先天性肛门直肠畸形的遗传因素和信号途径的研究现状

摘要/Abstract

摘要：

先天性肛门直肠畸形（ARM）发病率占消化道畸形首位，分为孤立性ARM和合并其他畸形的非孤立性ARM。目前研究表明，ARM是多基因遗传疾病，遗传因素在疾病发生发展中起到重要作用。文章就非孤立性ARM相关的遗传因素及潜在的信号转导途径作一综述。

沈玉洁, 综述，陈颖伟, 审校. 非孤立性先天性肛门直肠畸形的遗传因素和信号途径的研究现状[J]. 临床儿科杂志, 2014, 32(4): 388-391.

Reviewer: SHEN Yujie,Reviser: CHEN Yingwei. Research status of genetics and signaling pathways in non-isolated ARM　[J]. , 2014, 32(4): 388-391.

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非孤立性先天性肛门直肠畸形的遗传因素和信号途径的研究现状

Research status of genetics and signaling pathways in non-isolated ARM

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