临床儿科杂志 ›› 2021, Vol. 39 ›› Issue (6): 410-.doi: 10.3969/j.issn.1000-3606.2021.06.003

• 呼吸系统疾病专栏 • 上一篇    下一篇

产前糖皮质激素对晚期早产儿呼吸系统疾病的影响

王慧,曹丽芳,张雪峰   

  1. 北京大学国际医院儿科(北京 102206)
  • 出版日期:2021-06-15 发布日期:2021-05-31
  • 通讯作者: 张雪峰 电子信箱:doctor 1966 @sina.com

Effect of antenatal corticosteroids on respiratory diseases in late-preterm infant

WANG Hui, CAO Lifang, ZHANG Xuefeng   

  1. Department of Pediatrics, Peking University International Hospital, Beijing 102206, China
  • Online:2021-06-15 Published:2021-05-31

摘要: 目的 探讨产前激素应用对晚期早产儿呼吸系统疾病的影响。方法 回顾性分析2016年1月至2020年6月 娩出的晚期早产儿及其母亲的临床资料。根据母亲产前地塞米松应用情况分为激素组和对照组,比较不同胎龄晚期早产 儿呼吸系统疾病发生情况。采用logistic回归分析模型分析晚期早产儿生后呼吸系统疾病发生的危险因素。结果 在胎龄 36 ~ 36 + 6周组,激素组剖宫产率高于对照组;在胎龄35 ~ 35 + 6周和36 ~ 36 + 6周组,激素组母亲分娩前胎膜早破率低于对照 组,差异均有统计学意义(P

关键词: 呼吸系统疾病; 产前糖皮质激素; 晚期早产儿

Abstract: Objective To explore the effect of antenatal corticosteroids on respiratory diseases in late-preterm infants. Methods The clinical data of late-preterm infants delivered from January 2016 to June 2020 and their mothers were retrospectively analyzed. According to prenatal application of dexamethasone, the infants were divided into hormone group and control group, and the incidence of respiratory diseases in late preterm infants with different gestational ages was compared. Multivariate logistic regression analysis was used to analyze the risk factors of post-natal respiratory diseases in late preterm infants. Results In the gestational age group of 36 ~ 36+ 6 weeks, the rate of cesarean section in the hormone group was higher than that in the control group. In the gestational age group of 35 ~ 35+ 6 weeks and 36 ~ 36+ 6 weeks, the rate of premature rupture of membranes in the hormone group was lower than that in the control group, and the differences were statistically significant (P

Key words: respiratory diseases; antenatal corticosteroids; late-preterm infant