临床儿科杂志 ›› 2016, Vol. 34 ›› Issue (11): 834-.doi: 10.3969/j.issn.1000-3606.2016.11.008

• 综合报道 • 上一篇    下一篇

儿童髋关节一过性滑膜炎发病时间特征及与气候因素的相关性

赵天鑫 ,康权 ,董姿杏 ,吕凤香 ,仇超 ,罗庆   

  1. 重庆医科大学附属儿童医院儿科学重庆市重点实验室 儿科研究所儿童肿瘤研究室 儿童发育疾病 研究教育部重点实验室 儿童发育重大疾病国家国际科技合作基地(重庆 400014)
  • 收稿日期:2016-11-15 出版日期:2016-11-15 发布日期:2016-11-15
  • 通讯作者: 罗庆 E-mail:luoqing@cqmu.edu.cn
  • 基金资助:
    国家自然科学基金资助项目(No. 81172545);重庆市卫生和计划生育委员会医学科研项目(No. 2016MSXM039)

Transient synovitis of hip and effects of climate change on its prevalence in Chongqing

ZHAO Tianxin, KANG Quan, DONG Zixing, LYU Fengxiang, QIU Chao, LUO Qing   

  1. Chongqing Key Laboratory of Pediatric, Department of Pediatric Oncology, Institute of Pediatrics, Key Laboratory of Child Development and Disorders of Ministry of Education, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children’s Hospital of Chongqing Medical University, Chongqing 400014, China
  • Received:2016-11-15 Online:2016-11-15 Published:2016-11-15

摘要: 目的 探讨儿童髋关节一过性滑膜炎(TSH)发病的时间特征,及其发病情况与气候因素之间的联系。 方法 选取2008年至2012年收治的1 401例TSH患儿的临床资料,收集同期的月平均气温、月平均气压、月平均湿度、 月平均风速、月日照总时数和月总降水量等气象资料,采用卡方-拟合优度检验分析TSH发病的时间特征,运用相关分 析和逐步线性回归方法探讨TSH发病与各气象因素的关系。结果 TSH发病以春夏季为主(P < 0.001),3月份是发病 高峰(P < 0.001),10月份发病数最少(P < 0.001)。TSH的月发病数与月平均湿度呈负相关(r = −0.466, P < 0.001),与 月平均风速、月日照总时数呈正相关(r =0.286、0.262, P均 < 0.05);逐步回归分析中只有月平均湿度对进入回归模型 (β = −0.470, P < 0.001)。 结论 TSH的发病具有明显的时间周期性,在低湿度的气象条件下更容易发生。

Abstract: Objective To investigate the temporal pattern of the occurrence of transient synovitis of hip (TSH) and the correlation between the prevalence and climatic factors in Chongqing, China. Methods A total of 1401 cases of hospitalized children with TSH at Children’s Hospital of Chongqing Medical University between 2008 and 2013 were selected. Related climatic data consisting of air temperature, atmospheric pressure, relative humidity, wind velocity, sunshine duration, and precipitation in Chongqing were collected. Chi-square fitting test and multiple linear regression were used to test the temporal pattern of the occurrence of THS and the correlation between meteorological factors and the prevalence of TSH. Results Incidence of TSH was mainly occurred during spring and summer (P = 0.000), with a peak in March and a trough in October. TSH occurrence was negatively correlated with mean humidity per month (r =-0.466, P=0.000), and positively correlated with mean wind velocity and sum of sunshine per month (P =0.000, P =0.006, P =0.007). Stepwise regression analysis showed that only mean humidity per month fitted into a linear model (R2=0.229, P =0.000). Conclusions From 2008 to 2012, the prevalence of TSH in Chongqing showed seasonal and monthly periodicity. And the occurrence of TSH is correlated with climatic factors, particularly humidity.