目的　探讨冠状动脉异常起源主动脉的临床意义。方法　回顾分析1例疾病初期误诊为暴发性心肌炎、最终 诊断为冠状动脉异常起源主动脉患儿的临床资料，并复习相关文献。结果　患儿，女， 9岁，运动后出现晕厥；心肌酶谱增 高，肌钙蛋白阳性；心电图提示心肌缺血改变；心脏超声提示心功能下降。经积极治疗后，冠脉CT造影提示左冠状动脉起 源于右冠窦。结论　冠状动脉异常起源主动脉为临床较少见的心血管畸形，部分存在潜在的猝死风险。

　Objective　To explore the clinical significance of anomalous origin of coronary artery from the aorta. Methods　The clinical data of a case of anomalous origin of coronary artery from the aorta which was misdiagnosed as fulminant myocarditis in the early stage of the disease were retrospectively analyzed and relative literature were reviewed. Results　A 9-year-old girl had syncope after exercise and was found to have the significant elevation of myocardial enzyme and troponin. Electrocardiogram showed myocardial ischemia changes and the cardiac ultrasonography indicated decreased cardiac function. It was diagnosed as the left coronary artery from the right coronary sinus by the CT angiography. Conclusion　The anomalous origin of coronary artery is a rare cardiovascular malformation. Some patients have a potential risk of sudden death.