目的　探讨瞬目反射R1潜伏期在遗传性周围神经病（CMT）分型中的作用。方法　回顾分析确诊为CMT患 儿的临床资料，收集常规神经传导和瞬目反射的检查结果，记录尺神经运动传导速度，波幅和R1的潜伏期；并根据基因 检测结果将患儿分为脱髓鞘型组和轴突型组，比较两组间R1潜伏期差异。结果　共纳入36例CMT患儿，男20例、女16 例。其中脱髓鞘型24例，男14例、女10例；轴突型12例，男6例、女6例。脱髓鞘型组的R1潜伏期为（14.41±0.73）ms， 明显长于轴突型组的（11.39±0.89）ms，差异有统计学意义（P<0.01）；且脱髓鞘型组R1潜伏期均>13 ms，而轴突型组 均≤13 ms。在脱髓鞘型组中，尺神经波幅<0.5 mv患儿的R1可以稳定引出且潜伏期>13 ms。结论　瞬目反射R1潜伏期 > 13 ms为判断CMT脱髓鞘病变的可靠指标，且不受运动传导波幅影响；可指导基因检测。

　Objective　To investigate the utility of R1 latency of blink reflexes in typing of inherited polyneuropathy: Charcot-Marie-Tooth (CMT). Methods　Patients diagnosed with CMT by a genetic test underwent blink reflex testing and extremity NCS were retrospectively analyzed. Blink reflex R1 latency, extremity NCS, and severity were compared between demyelinating subtypes and axonal subtypes. Results　We included 24 demyelinating (14 males and 10 females) and 12 axonal (6 males and 6 females) CMT patients. R1-latency in demyelinating CMT group (14.41±0.73 ms) were longer than that in axonal CMT group (11.39±0.89 ms) (P<0.01). R1-latency were all >13 ms in demyelinating CMT group and ≤13 ms in axonal CMT group. Conclusions　Blink reflex test is reliable for identification of inherited demyelinating polyneuropathy regardless of severity and can guide genetic testing.