综合报道

注意缺陷多动障碍伴孤独症特征儿童社交相关行为问题及 执行功能研究#br#

  •  范云 ,
  •  张婷 ,
  •  冯蔚 ,
  •  舒艳 ,
  •  刘欣 ,
  •  陈亮亮 ,
  • 季忆婷 ,
  •  朱涛 ,
  •  李斐
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  • 1.上海交通大学医学院附属上海儿童医学中心发育行为儿保科(上海 200127);2.上海交通大学 医学院附属新华医院发育行为儿保科(上海 200092);3.环境与儿童健康教育部重点实验室、 上海市重点实验室(上海 200092)

收稿日期: 2018-08-15

  网络出版日期: 2018-08-15

基金资助

国家自然科学基金(No.81571031, No.81761128035, No.81781220701);上海市科委优秀学术带头人计划 (No.17XD1403200);上海市卫生计生系统项目(No.2017ZZ02026, No.2017EKHWYX-02, No.GDEK201709, No.2018BR33);上海市教委高原高峰计划(研究型医师项目,No.20152234);上海市申康三年行动计划项目 (No.16CR2025B )

The behavior characteristics and executive functions of ADHD children with autistic traits

  • FAN Yun ,
  • ZHANG Ting ,
  • FENG Wei ,
  • SHU Yan ,
  • LIU Xin ,
  • CHEN Liangliang ,
  •  JI Yiting ,
  • ZHU Tao ,
  • LI Fei
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  • 1.Department of Developmental Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China; 2.Child Health Care Department, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200029, China 3.MOE-Shanghai Key Laboratory of Children’s Environmental Health, Shanghai 200029, China

Received date: 2018-08-15

  Online published: 2018-08-15

摘要

目的 比较注意缺陷多动障碍(ADHD)伴孤独症特征(ATs)儿童和一般ADHD儿童临床特征及执行功能 的差异。方法 2015年12月至2017年1月收集ADHD患儿临床资料,根据其社交反应量表(SRS)得分,选择ADHD伴 ATs(ADHD-ATs组)80例和一般ADHD(ADHD组)95例;比较两组患儿SNAP-Ⅳ评定量表、Conners父母用症状问卷及 执行功能行为评定量表(BRIEF)的评估结果。结果 两组患儿的年龄、性别及智商差异无统计学意义(P>0.05)。 与 ADHD组比较,ADHD-ATs组SNAP-Ⅳ量表中多动核心症状、Conners问卷中的行为问题更明显,差异均有统计学意 义(P<0.05)。“ 冷”、“ 热”执行功能比较中,相较ADHD组,ADHD-ATs组的BRIEF得分均更高,心理理论(口语)得分 和总分更低,差异均有统计学意义(P<0.05)。 回归分析显示,“ 冷”、“ 热”执行功能与患儿社交行为问题有显著相关性 [BRIEF行为管理指数:β =-1.17, P<0.01,95%CI:- 2.00~-0.34;心理理论(口语):β =0.72, P<0.001,95%CI: 0.51~0.93]。结论 ADHD-ATs患儿较一般ADHD患儿的多动核心症状更为明显,执行功能上受损也更为严重。

本文引用格式

 范云 ,  张婷 ,  冯蔚 ,  舒艳 ,  刘欣 ,  陈亮亮 , 季忆婷 ,  朱涛 ,  李斐 . 注意缺陷多动障碍伴孤独症特征儿童社交相关行为问题及 执行功能研究#br#[J]. 临床儿科杂志, 2018 , 36(8) : 621 . DOI: 10.3969/j.issn.1000-3606.2018.08.014

Abstract

Objective To assess behavior characteristics and social functioning of children with attention-deficit/ hyperactivity disorder (ADHD)-autistic traits (ATs) and ADHD control (without ATs), and to explore the associations between the executive functions and the impairments of behavior. Method A total of 175 ADHD children diagnosed in the Departmen of Behavior Pediatrics in Shanghai Children's Medical Center and Xinhua Hospital were selected and divided into ADHD with autism traits (ADHD-ATs) group (n=80) and ADHD without autism traits (ADHD) group (n=95) by the scores of social response scale. All participants completed IQ test and questionnaires such as SNAP-Ⅳ, Conners Parent Symptom Questionnaire and Behavior Rating Inventory of Executive Function.  Results  There was no significant difference between the two groups in age, gender and IQ (P>0.05). ADHD-ATs children behaved worse in hyperactivity/impulsive behavior (P<0.05), worse impaired in theory of mind than ADHD children (P<0.05). Further regression analysis found that the impact of cold and hot executive functions had a significant relationship with social behavior problems (behavior management index: β =-1.17, P <0.05, 95% CI: -2.00~-0.34; theory of mind (oral): β =0.72, P<0.05, 95% CI:0.51~0.93). Conclusions Children with ADHD-ATs had more serious symptoms than children with ADHD, and with impaired cold and hot executive functions.
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