目的　探讨神经系统副肿瘤综合征（PNS）的临床特点。方法　回顾分析3例PNS患儿的临床表现、脑脊液检 查、生化指标、脑电图、头颅MRI及腹部影像学检查资料。结果　3例患儿中男性2例、女性1例，发病年龄2~6岁。均出现 神经系统症状，乳酸脱氢酶高，脑电图慢波增多，腹部影像学提示腹腔肿瘤； 1例脑脊液白细胞增高、寡克隆蛋白阳性； 2 例头颅MRI出现相应改变。结论　PNS起病隐匿，行脑脊液、乳酸脱氢酶、头颅MRI、腹部影像学等检查有助于早期诊治。

Objective　To investigate the clinical features of abdominal tumor with paraneoplastic neurological syndrome (PNS) in children. Methods　Clinical features, CSF test, peripheral blood test, EEG, brain MRI and abdominal imaging test of 3 cases with PNS were retrospectively reviewed. Results　The three patients (two boys and one girl) were diagnosed as PNS with onset of neurological symptoms. The average age of PNS patients were 3.7±1.7 years old. The level of LDH in peripheral blood was elevated. More slow waves occurred in EEG. Abdominal imaging test showed abdominal tumors. The white cell count of CSF test was higher than normal and oligoclonal protein was found positive in one case. Brain MRI showed corresponding changes in two cases. Conclusions　The onset of PNS was dormant. Early diagnosis through CSF tests, LDH, brain MRI and abdominal imaging tests can help abdominal tumor patients to get early treatment.