肥胖症儿童血清肿瘤坏死因子-α、白介素- 6、白介素- 1β、白介素-10和超敏C反应蛋白等炎症细胞因子和 炎性蛋白分泌异常，引起微炎症状态，影响动脉粥样硬化等心血管疾病的进程。研究表明，颈动脉结构异常，特别是颈动 脉内中膜厚度（cIMT）增加可早期提示动脉粥样硬化等心血管疾病发生的风险。文章综述肥胖症儿童微炎症状态和cIMT 的相关性。

Abnormal secretion of inflammatory cytokines and proteins such as tumor necrosis factor-α, interleukin- 6 , interleukin- 1 β, interleukin- 10 and hypersensitive C-reactive protein in serum of obese children leads to micro-inflammatory state and influences the progression of cardiovascular diseases such as atherosclerosis. Research shows that abnormal structure of carotid artery, especially the increase of carotid intima-media thickness (cIMT), can be early indication for the risk of atherosclerosis and other cardiovascular diseases. This article reviews the relationship between micro-inflammatory state and cIMT in obese children.