目的 探讨抗MOG抗体阳性皮质脑炎的临床特征。方法 回顾分析1例确诊MOG抗体阳性皮质脑炎患儿 的临床资料，并以“MOG”、“脑炎”为检索词，检索并复习近10年报道的相关病例。结果 女性患儿，10岁，以癫痫发作（局 灶性发作）为主要表现。颅脑磁共振成像（MRI）示额顶叶皮质受累。予抗癫痫药物及糖皮质激素治疗后临床症状及颅脑 MRI改变消失。结论 癫痫发作、发热及皮质综合征且头颅MRI示脑皮质损害者，应注意筛查MOG抗体。

Objective To investigate the clinical characteristics of anti-myelin oligodendrocyte glycoprotein (MOG)- associated cortical encephalitis. Methods The clinical data of a children with MOG seropositive cortical encephalitis were analyzed, “MOG” and “encephalitis” were used as keywords to retrieve and review the relevant cases reported in the past 10 years for analysis. Combined with 34 patients in the retrieved literature to summerize the clinical characteristics of antiMOG-associated cortical encephalitis. Results A 10 -year-old female patient mainly presented with epileptic seizures (focal seizures); brain magnetic resonance imaging (MRI) revealed frontal and parietal cortex involvement; the clinical symptoms and brain MRI changes disappeared after antiepileptic drug and glucocorticoid treatment. Conclusion For patients with epilepsy, fever, cortical syndrome and cortical damage by brain MRI, attention should be paid to screen MOG antibody