肺炎支原体疫苗研究进展
Research progress of Mycoplasma pneumoniae vaccine
Received date: 2021-09-13
Online published: 2022-08-09
张海情 , 陈艳萍 , 张瑾 . 肺炎支原体疫苗研究进展[J]. 临床儿科杂志, 2022 , 40(8) : 634 -640 . DOI: 10.12372/jcp.2022.21e1322
Mycoplasma pneumoniae (MP) is one of the main pathogens of community-acquired pneumonia, which can cause respiratory symptoms and other extrapulmonary complications. Macrolide antibiotics are the first choice for the treatment of MP infection. In recent years, with the increase of MP infection rate and the wide application of antibiotics, the situation of macrolide drug resistance is becoming more and more serious. Vaccine is the best scientific method to prevent and control the prevalence, infection and pathogenicity of germs. At present, animal MP vaccine has been marketed at home and abroad and achieved good protective effects, while MP vaccine for human is still in the research stage. Based on this, the MP related vaccine is reviewed in order to provide some reference for the development of human MP vaccine in the future.
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