长双歧杆菌与婴幼儿肠道健康的研究进展
Advances in Bifidobacterium longum and intestinal health during infancy
Received date: 2022-01-17
Online published: 2022-08-26
吴诗寅 , 蔡美琴 . 长双歧杆菌与婴幼儿肠道健康的研究进展[J]. 临床儿科杂志, 2022 , 40(9) : 715 -720 . DOI: 10.12372/jcp.2022.21e0107
Bifidobacterium longum is a commensal microbiota beneficial to the intestine, which is closely related to gut health during infancy. This paper reviews the physiological characteristics and the biological characteristics of genomics, metabolomics and proteomics, the prebiotic function in treating or alleviating gastrointestinal diseases in infants, and the research progress and application development prospect at home and abroad of Bifidobacterium longum. This review also analyzes the efficacy and possible mechanism of different strains of Bifidobacterium longum in the treatment of infantile functional constipation, irritable bowel syndrome and inflammatory bowel disease in order to provide scientific basis for the application of Bifidobacterium longum in clinical treatment or alleviation of gastrointestinal diseases in infants, and provide ideas for the development of Bifidobacterium longum functional strains and their in-depth research on promoting intestinal health.
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