新生儿糖尿病研究进展

陈虹; 张静

doi:10.3969 j.issn.1000-3606.2016.05.018

临床儿科杂志 >

2016 , Vol. 34 >Issue 5: 393

DOI: https://doi.org/10.3969 j.issn.1000-3606.2016.05.018

文献综述

新生儿糖尿病研究进展

陈虹 ,
张静

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1. 泉州医学高等专科学校临床医学系（福建泉州 362100）；2. 福建省福州儿童医院内分泌科福建医科大学教学医院（福建福州 350005）

收稿日期: 2016-05-15

网络出版日期: 2016-05-15

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Progress on neonatal diabetes mellitus

CHEN Hong ,
ZHANG Jing

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1. Department of Clinical Medicine, Quanzhou Medical College, Quanzhou, 362100, Fujian, China; 2. Department of Endocrionology, Fuzhou Children’s Hospital of Fujian, Fujian Medical University Teaching Hospital, Fuzhou 350005, Fujian, China

Received date: 2016-05-15

Online published: 2016-05-15

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摘要

大部分新生儿糖尿病（NDM）发柄与基因突变有关，部分NDM应用磺脲类药物治疗可取得良好疗效。新近研究从分子水平上阐明了NDM的发病机制及磺脲类药物的作用机制。另有研究表明糖化白蛋白是反映NDM血糖控制的有用指标。文章综述近年对NDM研究的进展。

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陈虹 , 张静 . 新生儿糖尿病研究进展[J]. 临床儿科杂志, 2016 , 34(5) : 393 . DOI: 10.3969 j.issn.1000-3606.2016.05.018

Abstract

Most neonatal diabetes mellitus (NDM) is caused by genetic abnormality. Sulfonylurea (SU) has been successfully applied in NDM patients; The pathogenesis of NDM and mechanism of sulfonylurea on molecular level have been illuminated, and recent studies revealed that glycated albumin is a useful glycemic indicator. In this review, the research progress of NDM is summarized.

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