贝达喹啉和德拉马尼在治疗儿童耐药结核病中的研究进展
收稿日期: 2022-08-08
网络出版日期: 2023-05-10
Advances in the study of bedaquiline and delamanid in the treatment of drug-resistant tuberculosis in children
Received date: 2022-08-08
Online published: 2023-05-10
王希羽 综述 , 许红梅 审校 . 贝达喹啉和德拉马尼在治疗儿童耐药结核病中的研究进展[J]. 临床儿科杂志, 2023 , 41(5) : 387 -393 . DOI: 10.12372/jcp.2023.22e1064
Tuberculosis (TB) is one of the major global public health concerns, and drug-resistant TB is one of the major obstacles to achieve the goal of ending TB due to the long treatment period, complicated regimens, multiple adverse effects and poor efficacy. In recent years, bedaquiline and delamanid have gradually become promising new drugs, but there is lack of researches on the application of these drugs in children with drug-resistant tuberculosis in China. This article reviews the efficacy and safety of bedaquiline and delamanid in drug-resistant tuberculosis and the progress of their use in children, in order to help construct new and effective regimens for the treatment of drug-resistant tuberculosis in children.
Key words： tuberculosis; drug-resistant tuberculosis; bedaquiline; delamanid; child
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