碳青霉烯类耐药铜绿假单胞菌耐药机制与治疗现状
Resistance mechanism and treatment of carbapenem resistant Pseudomonas aeruginosa
Received date: 2023-05-31
Online published: 2023-08-10
俞蕙 . 碳青霉烯类耐药铜绿假单胞菌耐药机制与治疗现状[J]. 临床儿科杂志, 2023 , 41(8) : 561 -565 . DOI: 10.12372/jcp.2023.23e0487
Pseudomonas aeruginosa is a common opportunistic pathogen of nosocomial infection, which is widely distributed in the hospital environment and can survive for a long time. Carbapenems antibiotics play an important role in the treatment of serious infections caused by Pseudomonas aeruginosa. However, the outbreak of carbapenems resistant Pseudomonas aeruginosa is particularly prominent in recent years, which has made clinical treatment facing great challenges. This article introduces the main resistance mechanism of Pseudomonas aeruginosa to carbapenems antibiotics and summarizes the application of various clinical treatment schemes, and provides a reference clinical rational use of antibiotics and treatment of carbapenems resistant Pseudomonas aeruginosa infection
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