儿童IgA血管炎肾炎预后危险因素分析

聂晓晶; 陈伊

doi:10.12372/jcp.2023.23e0697

临床儿科杂志 >

2023 , Vol. 41 >Issue 12: 895 - 902

DOI: https://doi.org/10.12372/jcp.2023.23e0697

专家笔谈

儿童IgA血管炎肾炎预后危险因素分析

聂晓晶 ,
陈伊

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福建医科大学福总临床医学院厦门大学附属东方医院联勤保障部队第九〇〇医院儿科（福建福州 350025）

聂晓晶，联勤保障部队第九○○医院儿科（全军儿科疾病诊治中心）科主任，副主任医师，医学博士，博士后，兼职教授，美国俄亥俄州立大学访问学者。兼任中华医学会儿科学分会青年委员、全军儿科学专业委员会青年委员、福建省医学会儿科学分会副主任委员。《中华儿科杂志》、《临床儿科杂志》通讯/青年编委；福建省卫生健康医学科技专家库、福州市医保基金监管专家库专家。荣立个人三等功2次，获军队优秀专业技术人才岗位津贴。被评为原第二军医大学“A级教员”、福建医科大学“最美教师”和“优秀教师”。承担国家自然科学基金、福建省引导性重点项目、福建省自然科学基金等课题9项。在SCI收录期刊和核心期刊发表论著30余篇。临床救治案例入选《中国临床案例成果数据库》。获福建省科学技术奖三等奖1项、发明专利3项。参与编写Causes and Diagnosis of Autoimmune Diseases、《军事儿科学》《新生儿重症监护医学》。专业特长儿童肾脏病和感染性疾病的诊断和治疗。ORCID：0000-0002-3144-1437

收稿日期: 2023-07-31

网络出版日期: 2023-12-04

基金资助

国家自然科学基金(81300583);福建省引导性（重点）、联合创新项目(2019Y0069);福建省引导性（重点）、联合创新项目(2019Y9043);福建省引导性（重点）、联合创新项目(2023Y0068);第九〇〇医院院内课题(2021MS15);第九〇〇医院院内课题(2021JQ10);第九〇〇医院院内课题(2022MS30);第九〇〇医院院内课题(2022ZD05)

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Analysis of prognostic risk factors of IgA vasculitis with nephritis in children

Xiaojing NIE ,
Yi CHEN

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Department of Pediatrics, Fuzong Clinical Medical College of Fujian Medical University, Affiliated Dongfang Hospital of Xiamen University, The 900th Hospital of Joint Logistic Support Force, Fuzhou 350025, Fujian, China

Received date: 2023-07-31

Online published: 2023-12-04

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摘要

IgA血管炎（IgA vasculitis，IgAV）是儿童时期最常见的全身性小血管炎，其累及肾脏时被称作IgAV肾炎（IgA vasculitis with nephritis，IgAVN），约20%IgAVN患者可发展为慢性肾脏病，其所致的儿童终末期肾病（ESRD）占ESRD病因构成的1%~2%。识别IgAVN预后的危险因素并及时给予有效干预，对改善患儿预后具有重要意义。本文就影响儿童IgAVN预后的危险因素进行阐述，以期为临床决策提供参考。

关键词： IgA血管炎; IgA血管炎肾炎; 预后; 危险因素; 儿童

本文引用格式

聂晓晶 , 陈伊 . 儿童IgA血管炎肾炎预后危险因素分析[J]. 临床儿科杂志, 2023 , 41(12) : 895 -902 . DOI: 10.12372/jcp.2023.23e0697

Abstract

IgA vasculitis (IgAV) is the most common systemic small vessel vasculitis in children, and it is called IgA vasculitis with nephritis (IgAVN) when it affects the kidneys. Renal damage eventually lead to chronic kidney disease in about 20% children with IgAVN, and accounting for 1%~2% of all childhood end-stage renal disease (ESRD). Therefore, it is important to identify the risk factors for the prognosis of IgAVN in children and give timely and effective intervention for the prognosis of IgAVN. This article reviews the risk factors affecting the prognosis of IgAVN in children, in order to provide reference for clinical decision-making.

Key words： IgA vasculitis; IgA vasculitis with nephritis; prognosis; risk factor; child

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