目的 探索胎儿心脏介入治疗（FCI）对于胎儿危重型先天性心脏病的可行性及短期疗效。方法 纳入2018年8月至2022年5月在宫内诊治中心进行FCI的所有患儿的临床资料，包括围产期至出生后基本信息、FCI手术信息、胎儿超声心动图信息等，追踪病例至出生后3月，分析FCI技术的可行性、有效性及安全性。结果 纳入胎儿7例，其中5例实施FCI手术，手术成功率100%（5/5），包括2例重度主动脉瓣狭窄（CAS）和3例室间隔完整型肺动脉闭锁（PA/IVS）。手术时的中位孕周为29⁺²（28⁺⁶~32⁺⁴）周。5例胎儿FCI术后的超声心动图指标均获得明显改善。5例胎儿均足月出生，中位出生胎龄39⁺²（38~39⁺⁴）周。生后2例CAS患儿行外科主动脉瓣成形术，3例PA/IVS患儿完成经皮肺动脉瓣球囊扩张术。1例心功能不全CAS患儿于新生儿期死亡，4例随访中，预后良好。结论 FCI是一项安全、有效的技术，有望改善危重型先天性心脏病的预后。

Objective To explore the feasibility and short-term efficacy of fetal cardiac intervention (FCI) for critical congenital heart disease. Methods The clinical data of all the fetuses who underwent FCI in the intrauterine diagnosis and treatment center from August 2018 to May 2022 were included, including basic information from perinatal to postnatal, FCI surgical information, fetal echocardiogram information, etc., and the fetuses were followed up until 3 months after birth to analyze the feasibility, effectiveness and safety of FCI technology. Results Seven fetuses were included, 5 of whom underwent FCI surgery with a 100% success rate (5/5), including 2 cases of critical aortic stenosis (CAS) and 3 cases of pulmonary atresia with intact ventricular septum (PA/IVS). The median gestational age at the time of FCI surgery was 29⁺²(28⁺⁶-32⁺⁴) weeks. The echocardiographic indexes of 5 fetuses after FCI were significantly improved. All five fetuses were full-term, with a median gestational age of 39⁺²(38-39⁺⁴) weeks. After birth, aortic valvuloplasty was performed in 2 patients with CAS and percutaneous balloon dilatation of pulmonary valve was performed in 3 patients with PA/IVS. One case of CAS with cardiac insufficiency died in the neonatal period, and the other 4 cases had good prognosis during follow-up. Conclusion FCI is a safe and effective technique that is expected to improve the prognosis of critical congenital heart disease.