儿童CAR-T细胞治疗的挑战与展望
Challenges and prospects of CAR-T treatment for pediatric disease
Received date: 2024-06-05
Online published: 2024-07-08
李本尚 , 杨柳 . 儿童CAR-T细胞治疗的挑战与展望[J]. 临床儿科杂志, 2024 , 42(7) : 573 -577 . DOI: 10.12372/jcp.2024.24e0578
It has been more than 10 years since chimeric antigen receptor T cells (CAR-T) therapy were first used to treat children with relapsed acute lymphoblastic leukemia, and thousands of patients worldwide have benefited from it. CAR-T treatment has greatly improved the overall prognosis of relapsed and refractory pediatric acute lymphoblastic leukemia patients and is gradually changing the treatment history of relapsed and refractory pediatric hematological tumor patients. Currently, CAR-T treatment for children still faces some challenges, but overall, the prospects are extremely promising.
Key words： chimeric antigen receptor T cell; challenge; prospect; child
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