健康生命轨迹计划缘起与发展:社区-家庭-母婴多层面儿童超重与肥胖干预研究队列
收稿日期: 2024-08-12
网络出版日期: 2024-09-04
基金资助
国家自然科学基金项目(82261128001);国家自然科学基金项目(81974235);国家重点研发计划(2018YFC1004602)
The origins and development of the healthy life trajectory program: a cohort of community-family-mother-child multidimensional interventions for overweight and obesity in children
Received date: 2024-08-12
Online published: 2024-09-04
健康生命轨迹计划(HeLTI)是由世界卫生组织(WHO)牵头,中国、加拿大、南非、印度等多个国家参与的前瞻性出生队列干预研究。本项目旨在利用HeLTI在个性化健康教育和权威专业健康指导方面的优势,探索建立涵盖备孕期、孕产期、婴幼儿期、学龄前期等多个阶段的社区-家庭-母亲-儿童(CFMC)干预措施,实施连续性多层面的干预,构建国际合作研究平台,实现从生命源头预防肥胖等发育源性疾病的目标。由中国、加拿大共同实施的中加健康生命轨迹计划(SCHeLTI)也称生命树项目,受中国国家自然科学基金委和加拿大卫生研究院共同资助,由国际和平妇幼保健院牵头,与上海交通大学医学院附属新华医院、复旦大学妇产科医院及加拿大舍布鲁克大学等知名大学和机构共同组成研究团队。项目纳入的研究对象主要来自上海市徐汇区、长宁区、闵行区、奉贤区、松江区的妇幼保健院及其管辖的42个社区卫生服务中心。本项目所采用的生命早期多层面综合干预方案将在上海地区乃至全国进行推广,研究结果期待为WHO制定儿童肥胖早期干预指南提供科学依据。
关键词: 生命树; 队列; 社区-家庭-母婴干预; 儿童肥胖
范建霞 . 健康生命轨迹计划缘起与发展:社区-家庭-母婴多层面儿童超重与肥胖干预研究队列[J]. 临床儿科杂志, 2024 , 42(9) : 768 -773 . DOI: 10.12372/jcp.2024.24e0818
The healthy life trajectories initiative (HeLTI) is a prospective birth cohort intervention study led by the World Health Organization (WHO), which involves multiple countries including China, Canada, South Africa, and India. The project aims to explore and establish community-family-maternal-child (CFMC) intervention measures that cover multiple stages such as pre-pregnancy, pregnancy, infancy and early childhood by the advantages of HeLTI in personalized health education and authoritative professional health guidance. It aims to implement continuous and multi-level interventions to build an international collaborative research platform, and to achieve the goal of preventing developmental diseases such as obesity from the earliest stage of life. The life tree project (Sino Canadian health life trajectories initiative, SCHeLTI) is jointly funded by the National Natural Science Foundation of China (NSFC) and the Canadian Institutes of Health Research (CIHR). It is led by the International Peace Maternal and Child Health Hospital, and has formed a research team with well-known universities and institutions such as Xinhua Hospital, Fudan University Obstetrics and Gynecology Hospital, and Sherbrooke University in Canada. The project is mainly implemented in 42 community health service centers in Xuhui District, Changning District, Minhang District, Fengxian District, and Songjiang District of Shanghai. The multi-level comprehensive interventions in this project will be promoted in Shanghai and even throughout the whole China, and provide scientific basis for WHO to develop intervention guidelines for childhood obesity.
[1] | Geserick M, Vogel M, Gausche R, et al. Acceleration of BMI in early childhood and risk of sustained obesity[J]. N Engl J Med, 2018, 379(14): 1303-1312. |
[2] | Song P, Yu J, Chang X, et al. Prevalence and correlates of metabolic syndrome in Chinese children: the China health and nutrition survey[J]. Nutrients, 2017, 9(1): 79. |
[3] | Zhu Y, Zheng H, Zou Z, et al. Metabolic syndrome and related factors in Chinese children and adolescents: analysis from a Chinese national study[J]. J Atheroscler Thromb, 2020, 27(6): 534-544. |
[4] | Zhao Z, Ding N, Song S, et al. Association between depression and overweight in Chinese adolescents: a cross-sectional study[J]. BMJ Open, 2019, 9(2): e024177. |
[5] | Wang S, Sun Q, Zhai L, et al. The prevalence of depression and anxiety symptoms among overweight/obese and non-overweight/non-obese children/adolescents in China: a systematic review and meta-analysis[J]. Int J Environ Res Public Health, 2019, 16(3): 340. |
[6] | Wang L, Kong L, Wu F, et al. Preventing chronic diseases in China[J]. Lancet, 2005, 366(9499): 1821-1824. |
[7] | Bergmeier H, Skouteris H, Horwood S, et al. Associations between child temperament, maternal feeding practices and child body mass index during the preschool years: a systematic review of the literature[J]. Obes Rev, 2014, 15(1): 9-18. |
[8] | Chaillet N, Dumont A, Abrahamowicz M, et al. A cluster-randomized trial to reduce cesarean delivery rates in Quebec[J]. N Engl J Med, 2015, 372(18): 1710-1721. |
[9] | Henderson M, Benedetti A, Barnett TA, et al. Influence of adiposity, physical activity, fitness, and screen time on insulin dynamics over 2 years in children[J]. JAMA Pediatr, 2016, 170(3): 227-235. |
[10] | Blake-Lamb TL, Locks LM, Perkins ME, et al. Interventions for childhood obesity in the first 1,000 days a systematic review[J]. Am J Prev Med, 2016, 50(6): 780-789. |
[11] | Hanson MA, Gluckman PD. Early developmental conditioning of later health and disease: physiology or pathophysiology?[J]. Physiol Rev, 2014, 94(4): 1027-1076. |
[12] | Boney CM, Verma A, Tucker R, et al. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus[J]. Pediatrics, 2005, 115(3): e290-e296. |
[13] | Gluckman PD, Hanson MA, Beedle AS. Early life events and their consequences for later disease: a life history and evolutionary perspective[J]. Am J Hum Biol, 2007, 19(1): 1-19. |
[14] | Gupta A, Osadchiy V, Mayer EA. Brain-gut-microbiome interactions in obesity and food addiction[J]. Nat Rev Gastroenterol Hepatol, 2020, 17(11): 655-672. |
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